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. 2024 Mar 1;14:5149. doi: 10.1038/s41598-024-55869-x

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Scatter plots of the bidirectional effects of type 2 diabetes mellitus (T2DM) with ulcerative colitis (UC) and Crohn's disease (CD). (A) Analysis of T2DM and UC. The X-axis shows the single nucleotide polymorphism (SNP) effect and SE (standard error) for each selected SNP from the T2DM genome-wide Pooled Association Study (GWA) dataset. The Y-axis shows SNP effects and SE on UC from the UC genome-wide Pooled Association Study (GWA) dataset. (B) Analysis of T2DM and CD. The X-axis shows the SNP effect and SE for each selected SNP from the GWA dataset for T2DM. The Y-axis is SNP effect and SE on CD from the GWA dataset of CD. (C) Analysis of UC and T2DM. The X-axis shows the SNP effect and SE for each selected SNP from the GWA dataset from UC. The Y-axis is the SNP effect and SE on T2DM from the GWA dataset for T2DM. (D) Analysis of CD and T2DM. The X-axis shows the SNP effect and SE for each selected SNP from the GWA dataset of CD. The Y-axis is the SNP effect and SE on T2DM from the GWA dataset for T2DM.