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. 2024 Mar 1;14:5128. doi: 10.1038/s41598-024-55867-z

Table 4.

Univariable analysis of factors associated with vaccination rejection (only factors that are likely to have a relationship of P < 0.10).

Factor Reject (n = 101) Accept (n = 299) Odds ratio (95% CI) P value
General information
 The highest level of education
 Below bachelor’s degree 62 (61.4%) 155 (51.8%) 1.45 (0.93–2.34) 0.096
 Bachelor’s degree or higher 39 (38.6%) 144 (48.2%) 1.00
 Reimbursement of medical expenses
  Direct disbursement 29 (28.7%) 73 (24.4%) 1.67 (0.95–2.94) 0.050
  Social security 35 (34.7%) 147 (49.2%) 1
  Health insurance 19 (18.8%) 33 (11.0%) 2.42 (1.23–4.75)
  Other (self-pay, private insurance) 18 (17.8%) 46 (15.4%) 1.64 (0.85–3.17)
 History of other vaccinations during pregnancy
  Influenza 46 (45.5%) 108 (36.1%) 1.48 (0.94–2.34) 0.092
  Diphtheria, tetanus, pertussis 36 (35.6%) 71 (23.7%) 1.78 (1.09–2.89) 0.020
  Other 1 (1.0%) 1 (0.3%) 2.98 (0.19–48.09) 0.442
  Have been infected with COVID-19 before pregnancy 30 (29.7%) 61 (20.4%) 1.65 (0.99–2.75) 0.054
Attitudes about COVID-19 infection
 You should not be vaccinated against COVID-19 infection during pregnancy
  Disagree 12 (11.9%) 131 (43.8%) 1  < 0.001
  Unsure 52 (51.5%) 127 (42.5%) 4.47 (2.28–8.77)
  Agree 37 (36.6%) 41 (13.7%) 9.85 (4.70–20.64)
 People have knowledge and understanding about the COVID-19 vaccine
  Disagree 1 (1.0%) 1 (0.3%) 1 0.054
  Unsure 32 (31.7%) 62 (20.7%) 0.52 (0.03–8.53)
  Agree 68 (67.3%) 236 (78.9%) 0.29 (0.02–4.67)
Attitudes about COVID-19 vaccination
 Vaccines can harm you
  Disagree 23 (22.8%) 130 (43.5%) 1  < 0.001
  Unsure 59 (58.4%) 156 (52.2%) 2.14 (1.25–3.65)
  Agree 19 (18.8%) 13 (4.3%) 8.26 (3.59–19.01)
 Vaccines cause harm to unborn babies
  Disagree 4 (4.0%) 65 (21.7%) 1  < 0.001
  Unsure 66 (65.3%) 204 (68.2%) 5.26 (1.85–14.98)
  Agree 31 (30.7%) 30 (10.0%) 16.79 (5.44–51.86)
 Vaccines raise your risk of miscarriage
  Disagree 10 (9.9%) 75 (25.1%) 1  < 0.001
  Unsure 61 (60.4%) 197 (65.9%) 2.32 (1.13–4.77)
  Agree 30 (29.7%) 27 (9.0%) 8.33 (3.60–19.30)
 Vaccines raise risk of premature birth
  Disagree 10 (9.9%) 75 (25.1%) 1  < 0.001
  Unsure 66 (65.3%) 196 (65.6%) 2.53 (1.23–5.17)
  Agree 25 (24.8%) 28 (9.4%) 6.70 (2.86–15.70)
 You should not be vaccinated while pregnant
  Disagree 11 (10.9%) 141 (47.2%) 1  < 0.001
  Unsure 38 (37.6%) 103 (34.4%) 4.73 (2.31–9.69)
  Agree 52 (51.5%) 55 (18.4%) 12.12 (5.89–24.93)
 Information on vaccination complications in pregnant women from social media influence vaccination decisions
  Disagree 1 (1.0%) 36 (12.0%) 19.75 (1.28–74.51) 0.001
  Unsure 26 (25.7%) 96 (32.1%) 15.95 (2.15–
  Agree 74 (73.3%) 167 (55.9%) 118.55)
 Vaccines can help reduce severity of illness
  Disagree 4 (4.0%) 8 (2.7%) 1 0.008
  Unsure 29 (28.7%) 46 (15.4%) 1.26 (0.35–4.57)
  Agree 68 (67.3%) 245 (81.9%) 0.56 (0.16–1.90)
 Vaccines given during pregnancy can increase the immunity of the unborn baby
  Disagree 10 (9.9%) 19 (6.4%) 1 0.091
  Unsure 62 (61.4%) 160 (53.5%) 0.74 (0.32–1.67)
  Agree 29 (28.7%) 120 (40.1%) 0.46 (0.19–1.09)
 Too frequent vaccinations will be dangerous to you
  Disagree 5 (5.0%) 30 (10.0%) 1 0.018
  Unsure 53 (52.5%) 184 (61.5%) 1.73 (0.64–4.67)
  Agree 43 (42.6%) 85 (28.4%) 3.04 (1.10–8.38)
 Too frequent vaccinations will cause harm to the unborn baby
  Disagree 3 (3.0%) 25 (8.4%) 1 0.006
  Unsure 50 (49.5%) 180 (60.2%) 2.32 (0.67–7.98)
  Agree 48 (47.5%) 94 (31.4%) 4.26 (1.22–14.81)
The decision to vaccinate against COVID-19
 COVID-19 vaccinations can help prevent infections and severe symptoms
  Know 79 (78.2%) 257 (86.0%) 1 0.027
  Don’t know 2 (2.0%) 12 (4.0%) 0.54 (0.12–2.47)
  Unsure 20 (19.8%) 30 (10.0%) 2.17 (1.17–4.03)
 Doctor or healthcare professional should explain to you that vaccination can reduce your risk of infection
  Should explain 87 (86.1%) 283 (94.6%) 1 0.005
  Don’t have to explain 14 (13.9%) 16 (5.4%) 2.85 (1.34–6.07)
 If you know that vaccination is helpful, will you receive injections or not?
  Get a vaccination of course 30 (29.7%) 208 (69.6%) 1  < 0.001
  Need to consult relatives first 38 (37.6%) 78 (26.1%) 3.38 (1.96–5.82)
  Don’t ask for a vaccination 33 (32.7%) 13 (4.3%) 17.60 (8.34–37.16)
 Reason for rejecting vaccination
  Fear of pain 1 (1.0%) 1 (0.3%) 2.98 (0.19–48.09) 0.419
  Fear of harming yourself 19 (18.8%) 29 (9.7%) 2.16 (1.01–1.61) 0.015
  Fear of harm to the unborn child 88 (87.1%) 233 (77.9%) 1.92 (1.01–3.65) 0.045
  Wanted to choose an alternative vaccine to the type allocated by the government 6 (5.9%) 53 (17.7%) 0.29 (0.12–0.70) 0.004
  Other 6 (5.9%) 7 (2.3%) 2.64 (0.86–8.03) 0.101
 If alternative vaccinations cost not much more, would you decide to be vaccinated?
  Would be vaccinated 39 (38.6%) 207 (69.2%) 1  < 0.001
  Would not be vaccinated 57 (56.4%) 75 (25.1%) 4.03 (2.48–6.56)
  Other 5 (5.0%) 17 (5.7%) 1.56 (0.54–4.48)
 You decided not to be vaccinated because the severity of COVID-19 is currently reducing
  Yes 30 (29.7%) 39 (13.0%) 1  < 0.001
  No 43 (42.6%) 197 (65.9%) 0.28 (0.16–0.51)
  Unsure 28 (27.7%) 63 (21.1%) 0.58 (0.30–1.11)
 You would like to know your immunity level before deciding to get vaccinated during pregnancy
  Yes 62 (61.4%) 221 (73.9%) 1 0.055
  No 17 (16.8%) 32 (10.7%) 1.89 (0.99–3.64)
  Unsure 22 (21.8%) 46 (15.4%) 1.71 (0.95–3.05)
 If you have low immunity level, you would decide to be vaccinated against COVID-19 during pregnancy
  Yes 34 (33.7%) 184 (61.5%) 1  < 0.001
  No 26 (25.7%) 31 (10.4%) 4.54 (2.40–8.58)
  Unsure 41 (40.6%) 84 (28.1%) 2.64 (1.57–4.56)
 Booking appointments for vaccinations is convenient
  Yes 43 (42.6%) 186 (62.2%) 1 0.001
  No 17 (16.8%) 44 (14.7%) 1.67 (0.87–3.20)
  Unsure 41 (40.6%) 69 (23.1%) 2.57 (1.55–4.28)
 It is difficult to book appointments for vaccinations
  Yes 18 (17.8%) 79 (26.4%) 1 0.008
  No 42 (41.6%) 146 (48.8%) 1.26 (0.68–2.34)
  Unsure 41 (40.6%) 74 (24.7%) 2.43 (1.28–4.61)
Grievances about decision to get vaccinated against COVID-19
 You felt embarrassed when your doctor advised you to get a vaccination
  Yes 35 (34.7%) 38 (12.7%) 1  < 0.001
  No 51 (50.5%) 222 (74.2%) 0.25 (0.14–0.43)
  Unsure 15 (14.9%) 39 (13.0%) 0.42 (0.20–0.89)
 You believed that your doctor would not provide standardized ante-natal care if you did not get vaccinated as recommended by the doctor
  Yes 24 (23.8%) 42 (14.0%) 1 0.020
  No 53 (52.5%) 201 (67.2%) 0.46 (0.26–0.83)
  Unsure 24 (23.8%) 56 (18.7%) 0.75 (0.38–1.50)
 The type of vaccine influences your vaccination decision
  Yes 64 (63.4%) 225 (75.3%) 1 0.046
  No 22 (21.8%) 50 (16.7%) 1.55 (0.87–2.74)
  Unsure 15 (14.9%) 24 (8.0%) 2.20 (1.09–4.44)