Table 5.
Three-month predictors of unacceptable pain and unacceptable pain with low inflammation, multivariate analysis.
| Variable | Basic model | Adj. for comorbidities |
|---|---|---|
| Unacceptable pain | ||
| 1 year after inclusion | ||
| Female sex | 1.58 (0.51, 4.86) | 1.64 (0.53, 5.14)a |
| HAQ | 2.44 (1.50, 3.95) | 2.40 (1.47, 3.92)a |
| Tender-swollen difference | 1.17 (0.78, 1.75) | 1.14 (0.75, 1.71)a |
| 2 years after inclusion | ||
| PGA | 3.02 (1.68, 5.43) | 2.79 (1.52, 5.12)b |
| Tender-swollen difference | 1.67 (0.87, 3.20) | 1.65 (0.86, 3.18)b |
| Unacceptable pain with low inflammation | ||
| 1 year after inclusion | ||
| Female sex | 5.57 (1.07, 28.83) | 5.14 (1.01, 26.17)b |
| PGA | 2.14 (1.16, 3.95) | 2.54 (1.44, 4.50)b |
| SJC28 | 1.56 (0.94, 2.58) | NIc |
| Tender-dominatedd | 6.18 (1.64, 23.27) | 3.58 (1.21, 10.62)b |
| 2 years after inclusion | ||
| PGA | 2.77 (1.54, 4.98) | 2.64 (1.44, 4.83)b |
| Tender-swollen difference | 1.64 (0.87, 3.11) | 1.63 (0.86, 3.07)b |
Both models include all variables in each sub-table. Results are presented as odds ratios (95% CI). Odds ratios are calculated per standard deviation for continuous variables. Unacceptable pain: VAS pain > 40. Low inflammation: CRP < 10.
NI: not included; PGA: patient global assessment; SJC28: swollen joint count in 28 joints.
a
Adjusted for other relevant comorbidities.
b
Adjusted for psychiatric comorbidities.
c
Excluded from this model due to limited power.
d
TJC28 > SJC28 × 1.5.