Table 3.
Adverse effects of berberine
| Study | Experimental group (n=) | Adverse effects (n=) | Adverse reaction symptom |
|---|---|---|---|
| Zhao et al. 2022 | 40 | 6 |
Nausea (n = 2) Diarrhea (n = 2) Drowsiness (n = 2) |
| Cao et al. (2012) | 38 | 9 |
Nausea (n = 3) Diarrhea Fatigue Constipation (n = 6) |
| Cui. (2016) | 40 | 15 |
Dizziness (n = 3) Fatigue (n = 4) Nausea (n = 5) Diarrhea (n = 3) |
| Ning et al. (2013) | 22 | 1 | Gastrointestinal reaction |
| Harrison et al. (0.5 g) (2021) | 33 | 9 |
Diarrhea (n = 4) Gastroesophageal reflux disease (n = 2) Nausea (n = 1) Headache (n = 2) |
| Harrison et al. (1 g) (2021) | 34 | 15 |
Diarrhea (n = 9) Gastroesophageal reflux disease (n = 0) Nausea (n = 15) Headache (n = 1) |