Table 2:
Baseline characteristics of patients with PAD, by number of uncontrolled risk factors
| Variable | None | 1 | 2 or more | p-value |
|---|---|---|---|---|
| N | 260 | 321 | 200 | |
| Risk Factor Control | ||||
| LDL ≥ 100 | 87 (27.1%) | 117 (58.5%) | < .001 | |
| HbA1c ≥ 7 | 89 (27.7%) | 102 (51.0%) | < .001 | |
| SBP ≥ 140 | 108 (33.6%) | 137 (68.5%) | < .001 | |
| Current Smoker | 37 (11.5%) | 83 (41.5%) | < .001 | |
| Symptom Severity | .009 | |||
| Asymptomatic | 103 (39.6%) | 114 (35.5%) | 54 (27.0%) | |
| IC | 116 (44.6%) | 129 (40.2%) | 94 (47.0%) | |
| CLTI | 41 (15.8%) | 78 (24.3%) | 52 (26.0%) | |
| Demographics | ||||
| Age (years), Mean (SD) | 74.15 (8.59) | 72.69 (10.84) | 70.07 (9.20) | < .001 |
| Age Category | < .001 | |||
| < 65 | 27 (10.4%) | 66 (20.6%) | 51 (25.5%) | |
| 65 - < 75 | 106 (40.8%) | 106 (33.0%) | 81 (40.5%) | |
| 75 - < 85 | 97 (37.3%) | 103 (32.1%) | 57 (28.5%) | |
| ≥ 85 | 30 (11.5%) | 46 (14.3%) | 11 (5.5%) | |
| Sex, Male | 166 (63.8%) | 189 (58.9%) | 113 (56.5%) | .25 |
| Race (RTI) | < .001 | |||
| White | 206 (79.2%) | 202 (62.9%) | 114 (57.0%) | |
| Black | 40–50 (15%−19%) | 105–115 (33%−36%) | 75–85 (38%−43%) | |
| Other/Unknown | * | * | * | |
| Medicaid Dual Enrollment | 30 (11.5%) | 72 (22.4%) | 47 (23.5%) | < .001 |
| Geographic-based | ||||
| Non-metropolitan area (vs. metro) | 48 (18.5%) | 64 (19.9%) | 40 (20.0%) | .88 |
| Household Income $, Median (Q1, Q3) | 56,100 (44,274, 75,971) | 55,204 (40,962, 72,616) | 53,750 (39,913, 64,483) | .02 |
| Medical History | ||||
| Prior Statins, yes | 229 (88.1%) | 265 (82.6%) | 164 (82.0%) | .11 |
| Comorbidities | ||||
| Cancer | 52 (20.0%) | 51 (15.9%) | 43 (21.5%) | .22 |
| Cerebrovascular disease | 103 (39.6%) | 94 (29.3%) | 73 (36.5%) | .03 |
| Chronic obstructive pulmonary disease | 98 (37.7%) | 120 (37.4%) | 74 (37.0%) | .99 |
| Congestive heart failure | 78 (30.0%) | 97 (30.2%) | 57 (28.5%) | .91 |
| Dementia | * | * | * | .13 |
| Diabetes mellitus | 112 (43.1%) | 177 (55.1%) | 133 (66.5%) | < .001 |
| Hypertension | 242 (93.1%) | 305 (95.0%) | 191 (95.5%) | .46 |
| Ischemic heart disease | 187 (71.9%) | 208 (64.8%) | 131 (65.5%) | .15 |
| Renal disease | 86 (33.1%) | 131 (40.8%) | 80 (40.0%) | .13 |
| Charlson score, Mean (SD) | 4.42 (2.80) | 5.01 (3.12) | 5.18 (2.89) | .01 |
*
Cell size of less than 11 removed in accordance with CMS cell suppression policy
HbA1c: Hemoglobin A1c; CLTI: chronic limb-threatening ischemia; IC: intermittent claudication; LDL: low density lipoprotein; SBP: systolic blood pressure