Table 2.
Associations of gaseous and particulate matter air pollutants and risk of death following breast cancer diagnosis, CA MEC breast cancer cases, 1993–2013a.
| All-cause mortality | Breast cancer mortality | CVD mortality | Non-breast cancer and non-CVD mortalityc | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Deaths | HR | 95% CI | p-value | Deaths | HR | 95% CI | p-value | Deaths | HR | 95% CI | p-value | Deaths | HR | 95% CI | p-value | ||
| LUR | NOxb | 981 | 1.16 | (0.96–1.40) | 0.12 | 418 | 1.25 | (0.93–1.66) | 0.13 | 240 | 1.60 | (1.08–2.37) | 0.02 | 323 | 0.91 | (0.64–1.30) | 0.61 |
| NO2b | 1005 | 1.14 | (0.91–1.43) | 0.25 | 428 | 1.34 | (0.95–1.90) | 0.09 | 245 | 1.49 | (0.92–2.40) | 0.11 | 332 | 0.81 | (0.53–1.22) | 0.31 | |
| Kriging | NOxb | 1095 | 1.16 | (0.96–1.39) | 0.13 | 461 | 1.27 | (0.96–1.68) | 0.09 | 269 | 1.37 | (0.93–2.02) | 0.12 | 365 | 0.93 | (0.67–1.29) | 0.65 |
| NO2b | 1111 | 1.25 | (1.00–1.57) | 0.05 | 468 | 1.45 | (1.02–2.07) | 0.04 | 269 | 1.58 | (0.99–2.51) | 0.06 | 374 | 0.94 | (0.64–1.38) | 0.75 | |
| PM2.5b | 1109 | 1.17 | (0.95–1.44) | 0.13 | 465 | 1.19 | (0.86–1.64) | 0.29 | 269 | 1.44 | (0.95–2.17) | 0.08 | 375 | 0.94 | (0.66–1.34) | 0.72 | |
| PM10b | 1112 | 1.13 | (1.00–1.29) | 0.06 | 468 | 1.20 | (0.98–1.48) | 0.09 | 269 | 1.25 | (0.97–1.62) | 0.09 | 375 | 0.96 | (0.77–1.21) | 0.75 | |
Adjusted for race/ethnicity, marital status, ERPR status, stage, grade, histology, tumor size, chemotherapy, hormone treatment, radiation, surgery, nSES at diagnosis and current nSES, BMI, smoking, alcohol, diabetes, CVD risk, and age at first live birth; and stratified by age at diagnosis
LUR and kriging per 50 ppb NOX; 20 ppb Kriging and LUR NO2; Kriging per 10ug/m3 PM10 and PM2.5
Distribution of cause of deaths: other cancer site than breast cancer (42%), diabetes (9%), chronic lower respiratory disease (9%), Alzheimer’s disease (8%), mental/behavioral disease (5%), pneumonia (5%), kidney disease (3%), liver disease (3%), infectious/parasitic disease (3%), other causes of deaths (5%), unknown cause (8%)