Table 3. Risk factors of kidney failure.

	Univariate			Age- & sex-adjusted
	HR	95% CI	p value	HR	95% CI	p value
Lab data
Creatinine	1.43	[1.25–1.62]	<0.001**	1.45	[1.27–1.66]	<0.001**
Hemoglobin	0.91	[0.81–1.02]	0.116	0.87	[0.77–0.99]	0.039*
CRP	0.98	[0.94–1.02]	0.237	0.98	[0.94–1.01]	0.208
Platelet	1.00	[1.00–1.00]	0.154	1.00	[1.00–1.00]	0.124
WBC	1.00	[1.00–1.00]	0.893	1.00	[1.00–1.00]	0.856
Total bilirubin	1.05	[0.96–1.16]	0.298	1.07	[0.97–1.18]	0.172
Albumin	0.71	[0.46–1.10]	0.128	0.72	[0.46–1.13]	0.151
Galactomannan test
Blood-first	1.29	[1.13–1.48]	<0.001**	1.27	[1.11–1.46]	0.001**
Blood-max	1.14	[1.02–1.28]	0.026*	1.13	[1.01–1.27]	0.037*
BAL-first	1.17	[1.02–1.33]	0.025*	1.18	[1.03–1.35]	0.018*
BAL-max	1.16	[1.02–1.33]	0.028*	1.17	[1.02–1.34]	0.021*
Comorbidity
COPD	1.13	[0.48–2.64]	0.786	0.99	[0.40–2.46]	0.980
Asthma	1.40	[0.66–2.99]	0.380	1.36	[0.63–2.93]	0.438
Liver cirrhosis	2.51	[0.78–8.10]	0.125	2.67	[0.81–8.82]	0.107
DM	2.24	[1.23–4.06]	0.008**	2.07	[1.12–3.82]	0.021*
Hematological disease	0.43	[0.25–0.77]	0.004**	0.44	[0.25–0.79]	0.006**
Solid organ malignancy	0.91	[0.44–1.87]	0.792	0.82	[0.39–1.72]	0.597
Liver or kidney transplant	3.07	[1.30–7.27]	0.011*	3.45	[1.37–8.65]	0.008**
IPA groups
Possible IPA	Reference			Reference
Probable IPA	2.18	[1.13–4.21]	0.020*	2.17	[1.12–4.20]	0.021*
Proven IPA	0.51	[0.11–2.23]	0.368	0.45	[0.10–2.01]	0.295
Putative IPA	3.96	[1.73–9.05]	0.001**	3.41	[1.45–8.01]	0.005**

Notes:

Cox proportional hazard regression.

^*p < 0.05.

^**p < 0.01.

CRP, C-reactive protein; WBC, white blood cell; BAL, bronchial alveolar lavage; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; IPA, invasive pulmonary aspergillosis.