. 2024 Feb 28;12:e17062. doi: 10.7717/peerj.17062

Table 4. Biomarkers of stress oxidative and cytokines levels in the stomach of rats fed with a diet high in fat and sugar and administered with indomethacin.

	Leptin (mg/dl)	Adiponectin (mg/dl)	AOPP (µmol/L)	IL-6 (mg/dl)	TNFα (mg/dl)	MDA (nM//mg protein)	HNE (nM/mg protein)	p(*)
Control	304. 2 ± 12.8^C*	27.3 ± 0.9^A	3.8 ± 0.1^B	90.4 ± 5.9^B	2197.2 ± 28.2^C*	0.05 ± 0.009^B	0.05 ± 0.01^B	D × I
HFSD + Ind	904.7 ± 12.8^A*	13.9 ± 0.9^B*	6.4 ± 0.1^A*	179.5 ± 6.9^A*	3489.4 ± 28.2^A*	0.19 ± 0.009^A*	0.15 ± 0.01^A*	D × I
*HFSD + C. citrinus* + Ind**	454.6 ± 12.8^B	31.0 ± 0.9^A	2.2 ± 0.1^C*	116.6 ± 6.9^B	3058.9 ± 28.2^B	0.08 ± 0.009^B	0.07 ± 0.01^B	D × I
Indomethacin (Ind)	430.1 ± 14.4^A*	17.6 ± 0.2^B*	4.9 ± 0.1^A*	121.7 ± 6.4^B*	2455.7 ± 76.5^B*	0.14 ± 0.005^A*	0.09 ± 0.01^A*	I
C. citrinus + Ind	348.8 ± 14.4^B	12.3 ± 0.2^C*	3.6 ± 0.1^B	97. 6 ± 6.4^B	2445.0 ± 76.5^B	0.12 ± 0.005^A,B	0.06 ± 0.01^B	I
Omeprazole + Ind	490.9 ± 14.4^A	19.4 ± 0.2^A	4.8 ± 0.1^A	154.2 ± 6.4^A	4410.5 ± 76.5^A	0.11 ± 0.005^B	0.03 ± 0.01^C*	I

Note:

Data shown as mean ± S.E.M. (ANOVA one-way followed by Tukey test, values statistically different (^A,B,C) among groups (*p < 0.05), n = 6). D, diet; I, indomethacin; D × I, Diet × indomethacin.