Table 2.
Tukey’s HSD post hoc pairwise analysis of cardiac function in 3.5- and 11.5-mo-old female mouse offspring
| Maternal Diet |
||
|---|---|---|
| 3.5-mo offspring age | 11.5-mo offspring age | P Value |
| Average heart rate | ||
| CD | CD | 0.0061** |
| CD | FADD | 0.0027** |
| CD | ChDD | 0.0028** |
| FADD | CD | 0.9755 |
| FADD | FADD | 0.8215 |
| FADD | ChDD | 0.8263 |
| ChDD | CD | 0.9290 |
| ChDD | FADD | 0.7478 |
| ChDD | ChDD | 0.7525 |
| Average stroke volume | ||
| CD | CD | 0.9985 |
| CD | FADD | 0.2006 |
| CD | ChDD | 0.9997 |
| FADD | CD | >0.9999 |
| FADD | FADD | 0.0426* |
| FADD | ChDD | 0.9331 |
| ChDD | CD | 0.8983 |
| ChDD | FADD | 0.6806 |
| ChDD | ChDD | 0.9978 |
| CD | CD | 0.9985 |
| Average ejection fraction | ||
| CD | CD | 0.9993 |
| CD | FADD | 0.1809 |
| CD | ChDD | 0.1476 |
| FADD | CD | >0.9999 |
| FADD | FADD | 0.2741 |
| FADD | ChDD | 0.2275 |
| ChDD | CD | 0.9997 |
| ChDD | FADD | 0.2825 |
| ChDD | ChDD | 0.2493 |
| Average cardiac output | ||
| CD | CD | 0.0020* |
| CD | FADD | 0.0057* |
| CD | ChDD | 0.0036* |
| FADD | CD | 0.0355* |
| FADD | FADD | 0.0825 |
| FADD | ChDD | 0.0543 |
| ChDD | CD | 0.0245* |
| ChDD | FADD | 0.0499* |
| ChDD | ChDD | 0.0343* |
Maternal diets included control diet (CD), folic acid-deficient diet (FADD), and choline-deficient diet (ChDD). HSD, honestly significant difference. P values are of 5 to 7 mice/group.
*
P < 0.05; **P < 0.01, post hoc pairwise comparison.