Table 3.
Multiple regression assessing interactions between age and sex on aortic stiffness, carotid pulse pressure, and carotid stiffness
| cf Pulse Wave Velocitya |
CCA Pulse Pressureb |
CCA β-Stiffnessc |
||||
|---|---|---|---|---|---|---|
| B (95% CI) | β | B (95% CI) | β | B (95% CI) | β | |
| Age | 0.01 (−0.04,0.06) | 0.13 | −0.85 (−1.26,−0.45) | −1.22** | 0.06 (−0.03, 0.14) | 0.32 |
| Age2 | 0.001 (0.00,0.001) | 0.48* | 0.01 (0.002,0.01) | 0.83* | 0.00 (−0.001, 0.001) | 0.13 |
| Female sex | 0.40 (−0.25,1.04) | 0.11 | −21.82 (−27.22,−16.42) | −1.00** | −1.48 (−2.64, −0.31) | −0.28* |
| Sex × age | −0.02 (−0.03,−0.001) | −0.21* | 0.44 (0.32,0.55) | 0.98** | 0.03 (0.004, 0.06) | 0.27* |
| BMI | 0.03 (−0.003,0.06) | 0.06 | −0.32 (−0.55,−0.08) | −0.12* | −0.05 (−0.10, 0.001) | −0.08 |
| MAP | 0.05 (0.04,0.06) | 0.28** | 0.46 (0.36,0.57) | 0.41** | 0.05 (0.03, 0.07) | 0.18** |
| Adjusted R2 | 0.58 | 0.25 | 0.42 | |||
| F statistic | 72.13 | 18.42 | 39.16 | |||
Participants were studied with aortic stiffness (n = 417), carotid pulse pressure (n = 419), and carotid stiffness (n = 418). aMen, n = 203; women, n = 214. bMen, n = 203; women, n = 216. cMen, n = 202; women, n = 216. Antihypertensive therapy and statin therapy use included as covariates in model but are not reported. B, unstandardized beta weight; CCA, common carotid artery; CI, confidence interval; BMI, body mass index; MAP, mean arterial pressure. Significant predictor at *P < 0.05 and **P ≤ 0.001.