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. 2023 Sep 8;325(5):H1059–H1068. doi: 10.1152/ajpheart.00351.2023

Table 2.

Hemodynamic and gas exchange variables during the cerebrovascular reactivity to hypercapnia test

Sham
IMST
Baseline Posttesting Baseline Posttesting
Normocapnia
 MCAv, cm/s 25.5 ± 6.8# 31.1 ± 3.8# 49.5 ± 17.6 45.2 ± 14.3
 CVCi, cm/s/mmHg 0.27 ± 0.07# 0.30 ± 0.04 0.49 ± 0.22 0.43 ± 0.17
 MCA pulsatility index, AU 1.46 ± 0.82 1.27 ± 0.70 1.14 ± 0.39 1.00 ± 0.18
 MAP, mmHg 108 ± 6 106 ± 6 108 ± 12 108 ± 14
PETCO2, mmHg 36.0 ± 3.9 38.6 ± 2.9 37.5 ± 1.7 37.1 ± 5.1
Hypercapnia
 MCAv, cm/s 37.4 ± 6.3# 42.5 ± 8.0# 61.8 ± 23.1 63.3 ± 16.6
 CVCi, cm/s/mmHg 0.34 ± 0.08# 0.38 ± 0.06# 0.57 ± 0.25 0.55 ± 0.20
 MCA pulsatility index, AU 1.29 ± 0.64 1.04 ± 0.34 0.98 ± 0.28 0.87 ± 0.15
 MAP, mmHg 115 ± 6 114 ± 10 113 ± 11 117 ± 15*
PETCO2, mmHg 45.4 ± 3.4 46.4 ± 2.8 46.3 ± 1.9 45.5 ± 3.4

Values are means ± SD. Data were collected with participants in the semirecumbent position. MCAv, middle cerebral artery blood velocity; CVCi, cerebrovascular conductance index; AU, arbitrary units; MAP, mean arterial pressure; PETCO2, end-tidal pressure of carbon dioxide. Statistics are 2-way repeated-measures ANOVA with Fisher’s least significant difference post hoc analysis. *P < 0.05 vs. within-group baseline; #P < 0.05 vs. inspiratory muscle strength training (IMST) at matched time point.