Table 2.
Hemodynamic and gas exchange variables during the cerebrovascular reactivity to hypercapnia test
| Sham |
IMST |
|||
|---|---|---|---|---|
| Baseline | Posttesting | Baseline | Posttesting | |
| Normocapnia | ||||
| MCAv, cm/s | 25.5 ± 6.8# | 31.1 ± 3.8# | 49.5 ± 17.6 | 45.2 ± 14.3 |
| CVCi, cm/s/mmHg | 0.27 ± 0.07# | 0.30 ± 0.04 | 0.49 ± 0.22 | 0.43 ± 0.17 |
| MCA pulsatility index, AU | 1.46 ± 0.82 | 1.27 ± 0.70 | 1.14 ± 0.39 | 1.00 ± 0.18 |
| MAP, mmHg | 108 ± 6 | 106 ± 6 | 108 ± 12 | 108 ± 14 |
| , mmHg | 36.0 ± 3.9 | 38.6 ± 2.9 | 37.5 ± 1.7 | 37.1 ± 5.1 |
| Hypercapnia | ||||
| MCAv, cm/s | 37.4 ± 6.3# | 42.5 ± 8.0# | 61.8 ± 23.1 | 63.3 ± 16.6 |
| CVCi, cm/s/mmHg | 0.34 ± 0.08# | 0.38 ± 0.06# | 0.57 ± 0.25 | 0.55 ± 0.20 |
| MCA pulsatility index, AU | 1.29 ± 0.64 | 1.04 ± 0.34 | 0.98 ± 0.28 | 0.87 ± 0.15 |
| MAP, mmHg | 115 ± 6 | 114 ± 10 | 113 ± 11 | 117 ± 15* |
| , mmHg | 45.4 ± 3.4 | 46.4 ± 2.8 | 46.3 ± 1.9 | 45.5 ± 3.4 |
Values are means ± SD. Data were collected with participants in the semirecumbent position. MCAv, middle cerebral artery blood velocity; CVCi, cerebrovascular conductance index; AU, arbitrary units; MAP, mean arterial pressure; , end-tidal pressure of carbon dioxide. Statistics are 2-way repeated-measures ANOVA with Fisher’s least significant difference post hoc analysis. *P < 0.05 vs. within-group baseline; #P < 0.05 vs. inspiratory muscle strength training (IMST) at matched time point.