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. 2024 Jan 28;21(1):90–103. doi: 10.26599/1671-5411.2024.01.004

Table 5. Clinical outcomes with different CYP2C19 genotypes at one year follow-up.

Adverse Events Normal metabolizer (n = 272) Intermediate metabolizer (n = 281) Poor metabolizer (n = 62) P-value
Values expressed are in n (%). MACCEs major adverse cardiac and cerebrovascular event, includes cardiac death, stent thrombosis, repeat revascularization, MI and stroke, MI myocardial infarction. MI: myocardial infarction. aP < 0.05 vs. NCLR group, bP < 0.05 vs. Ticagrelor group, cP < 0.05 vs. Clopidogrel group..
All-cause death 5 (1.8%) 6 (2.1%) 1 (1.6%) 0.948
MACCEs 29 (10.7%) 46a (16.4%) 14a (22.6%) 0.026
Cardiac death 4 (1.5%) 4 (1.4%) 1 (1.6%) 0.994
Stent thrombosis 10 (3.7%) 15 (5.3%) 4 (6.5%) 0.519
MI 6b,c (2.2%) 13a,c (4.6%) 6ab (9.7%) 0.034
Repeat revascularization 9 (3.3%) 12 (4.3%) 2 (3.2%) 0.817
Stroke 0 (-) 2 (0.7%) 1 (1.6%) 0.141
Massive bleeding 3 (1.1%) 4 (1.4%) 1 (1.6%) 0.922
Moderate bleeding 13 (4.8%) 4 (1.4%) 3 (4.8%) 0.051
Small bleeding 19 (7.0%) 24 (8.5%) 4 (6.5%) 0.736