Table 5. Clinical outcomes with different CYP2C19 genotypes at one year follow-up.
| Adverse Events | Normal metabolizer (n = 272) | Intermediate metabolizer (n = 281) | Poor metabolizer (n = 62) | P-value |
| Values expressed are in n (%). MACCEs major adverse cardiac and cerebrovascular event, includes cardiac death, stent thrombosis, repeat revascularization, MI and stroke, MI myocardial infarction. MI: myocardial infarction. aP < 0.05 vs. NCLR group, bP < 0.05 vs. Ticagrelor group, cP < 0.05 vs. Clopidogrel group.. | ||||
| All-cause death | 5 (1.8%) | 6 (2.1%) | 1 (1.6%) | 0.948 |
| MACCEs | 29 (10.7%) | 46a (16.4%) | 14a (22.6%) | 0.026 |
| Cardiac death | 4 (1.5%) | 4 (1.4%) | 1 (1.6%) | 0.994 |
| Stent thrombosis | 10 (3.7%) | 15 (5.3%) | 4 (6.5%) | 0.519 |
| MI | 6b,c (2.2%) | 13a,c (4.6%) | 6ab (9.7%) | 0.034 |
| Repeat revascularization | 9 (3.3%) | 12 (4.3%) | 2 (3.2%) | 0.817 |
| Stroke | 0 (-) | 2 (0.7%) | 1 (1.6%) | 0.141 |
| Massive bleeding | 3 (1.1%) | 4 (1.4%) | 1 (1.6%) | 0.922 |
| Moderate bleeding | 13 (4.8%) | 4 (1.4%) | 3 (4.8%) | 0.051 |
| Small bleeding | 19 (7.0%) | 24 (8.5%) | 4 (6.5%) | 0.736 |