Table 4.

Multivariate logistic regression analysis for disease recurrence

Multivariate binary logistic regression: disease recurrence	OR	CI	P value
Grade
1–2 (ref)	–	–	–
3–4	1.3	0.98–1.73	0.068
R1	1.05	0.65–1.69	0.838
Perineural invasion	1.23	0.94–1.62	0.129
Staging
Ia/Ib (ref)	–	–	–
IIa/IIb	1.75	1.31–2.35	<0.001
III	3.18	2.03–4.97	<0.001
NAT	0.79	0.59–1.07	0.122
I-IPMN	0.37	0.23–0.59	<0.001

Multivariate Cox regression: survival	HR	CI	P value
Grade
1–2 (ref)	–	–	–
3–4	1.37	1.17–1.62	<0.001
R1	1.2	0.95–1.53	0.135
Perineural invasion	0.98	0.83–1.15	0.805
Staging
Ia/Ib (ref)	–	–	–
IIa/IIb	1.61	1.33–1.94	<0.001
III	2.64	2.09–3.32	<0.001
NAT	0.83	0.7–0.99	0.041
I-IPMN	0.55	0.39– 0.76	<0.001
Vascular resection	1.34	1.13–1.59	<0.001

Bold values indicate statistically significant results (p < 0.05)

NAT = neoadjuvant therapy, I-IPMN = invasive intraductal mucinous cystic neoplasm, OR = odds ratio, HR = hazard ratio, CI = confidence interval