Table 2.
PD-1 and PD-L1 levels in LP patients and controls
| LP patients | 95% Confidence interval | Control | P value | |||
|---|---|---|---|---|---|---|
| Mean ± SD | Lower bound | Upper bound | Cutoff level | Mean ± SD | ||
| Lesional PD-1 (ng/mg protein) | 3.00 ± 1.37 | 1.000 | 1.000 | < 6 | 9.72 ± 1.69 | < 0.001* |
| Nonlesional PD-1 (ng/mg protein) | 5.58 ± 2.35 | 0.840 | 0.983 | < 7.35 | 9.72 ± 1.69 | < 0.001* |
| P value | < 0.001* | |||||
| Lesional PD-L1 (ng/mg protein) | 0.98 ± 0.51 | 1.000 | 1.000 | < 2.15 | 4.09 ± 1.02 | < 0.001* |
| Nonlesional PD-L1 (ng/mg protein) | 1.97 ± 0.74 | 0.917 | 1.000 | < 2.75 | 4.09 ± 1.02 | < 0.001* |
| P value | < 0.001* | |||||
LP: lichen planus, SD: standard deviation, PD-1: programmed cell death protein-1, PD-L1: Programmed cell death ligand-1,*P < 0.001 is highly significant