Fig. 4.

LSD1 and riboflavin receptors are increased in M2 macrophages under inflammatory stimuli. A LSD1 expression in monocytes differentiates into M2 macrophages exposed to TNFα (20 ng/ml) for 18 h. B LSD1 expression in monocytes differentiates into M2 macrophages exposed to TGFβ (10 ng/ml) for 18 h. C Riboflavin receptors (SLC52A2 and SLC52A3) expressions in M2 macrophages exposed to TNFα (20 ng/ml) or TGFβ (10 ng/ml) for 18 h. D Riboflavin receptors (SLC52A2 and SLC52A3) expressions in M1, M2, and M2 exposed to TNFα (20 ng/ml) or TGFβ (10 ng/ml) for 18 h. Gene expressions were normalized using GAPDH as a housekeeping gene. Data are represented as mean ± SD of the average of three biological replicates. **p < 0.01; ***p < 0.001 Mann–Whitney test when comparing two groups. *p < 0.05; **p < 0.01 One-way ANOVA when comparing three groups