Table 2.
In vivo anthelmintic effect of PLE* on adult stages of H. diminuta (n = 6)
| Groups | EPG (mean ± S.E.M.) | Percentage difference in EPG (A-B) | Worms recovered/rat (mean ± S.E.M.) | Percentage reduction in worm counts | |
|---|---|---|---|---|---|
| Pre-treatment days 18−20 (A) | Post-treatment days 26−28 (B) | ||||
| Control | 22,977 ± 377 | 235 ± 389d | + 1.11 | 3.67 ± 0.21 | 8.25 |
| Plant extract | |||||
| 200 mg/kg | 21,581 ± 274 | 11,294 ± 302c | − 47.67 | 2.33 ± 0.21a | 41.75 |
| 400 mg/kg | 21,083 ± 292 | 9533 ± 178c | − 54.78 | 1.67 ± 0.21b | 58.50 |
| 800 mg/kg | 20,511 ± 155 | 7556 ± 149c | − 63.16 | 1.33 ± 0.21b | 66.75 |
| Praziquantel | |||||
| 10 mg/kg | 21,944 ± 190 | 2492 ± 75c | − 88.64 | 0.67 ± 0.33b | 83.25 |
*Administration of plant extract and praziquantel on days 21 − 25 post inoculation with four cysticercoids/rat
ap < 0.01 as compared to control value, one way ANOVA
bp < 0.001 as compared to control value, one way ANOVA
cp < 0.001 as compared to pre-treatment value, one way ANOVA
dp > 0.05 as compared to pre-treatment value, one way ANOVA