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. 2023 Nov 27;48(1):26–32. doi: 10.1007/s12639-023-01636-0

Table 2.

In vivo anthelmintic effect of PLE* on adult stages of H. diminuta (n = 6)

Groups EPG (mean ± S.E.M.) Percentage difference in EPG (A-B) Worms recovered/rat (mean ± S.E.M.) Percentage reduction in worm counts
Pre-treatment days 18−20 (A) Post-treatment days 26−28 (B)
Control 22,977 ± 377 235 ± 389d  + 1.11 3.67 ± 0.21 8.25
Plant extract
200 mg/kg 21,581 ± 274 11,294 ± 302c − 47.67 2.33 ± 0.21a 41.75
400 mg/kg 21,083 ± 292 9533 ± 178c − 54.78 1.67 ± 0.21b 58.50
800 mg/kg 20,511 ± 155 7556 ± 149c − 63.16 1.33 ± 0.21b 66.75
Praziquantel
10 mg/kg 21,944 ± 190 2492 ± 75c − 88.64 0.67 ± 0.33b 83.25

*Administration of plant extract and praziquantel on days 21 − 25 post inoculation with four cysticercoids/rat

ap < 0.01 as compared to control value, one way ANOVA

bp < 0.001 as compared to control value, one way ANOVA

cp < 0.001 as compared to pre-treatment value, one way ANOVA

dp > 0.05 as compared to pre-treatment value, one way ANOVA