Table 1.
p53 and CK19 expression in Normal (group I) and OSCC (group II)
| Staining Status (p53) | Groups [Number (%)] | P-value* | |
|---|---|---|---|
| Normal (n = 40) | OSCC (n = 45) | ||
| Negative | 6 (15%) | 15 (33.33%) | 0.05(S) |
| Positive | 34 (85%) | 30 (66.67%) | |
| Percentage positive cells (p53) | < 0.0001 (HS) | ||
| Mean ± SD | 16.00 ± 5.20 | 45.57 ± 26.47 | |
| Staining Intensity (p53) | |||
| No positivity found | 6 (15%) | 15 (33.3%) | < 0.0001 (HS) |
| Positivity only at 40x | 4 (10%) | 3 (6.67%) | |
| Positivity obvious at 10x not at 4x | 29 (67.5%) | 2 (4.44%) | |
| Positivity obvious at 4x | 1 (2.5%) | 25 (55.56%) | |
| Staining Index (p53) | < 0.0001 (HS) | ||
| Zero (Absent) | 6 (15.0%) | 15 (33.33%) | |
| Low | 33 (82.5%) | 5 (11.11%) | |
| Medium | 1 (2.5%) | 7 (15.56%) | |
| High | 0 | 18 (40.00%) | |
| Mean ± SD | 1.87 ± 0.34 | 5.63 ± 3.02 | |
| Staining Status (CK 19) | |||
| Negative | 33 (82.5) | 43 (95.56) | 0.1097 (NS) |
| Positive | 7 (17.5) | 2 (4.44) | |
|
Percentage positive cells (CK 19) |
|||
| Mean ± SD | 18.29 ± 4.11 | 41.00 ± 7.07 |
0.1122 (NS) |
| Staining Intensity (CK19) | |||
| No positivity found | 33(82.5%) | 43(95.56%) | |
| Positivity only at 40x | 3 (7.5%) | 0 | |
| Positivity obvious at 10x not at 4x | 4 (10%) | 0 | |
| Positivity obvious at 4x | 0 | 2 (4.44%) | |
| Staining Index (CK19) | |||
| Zero (absent) | 33 (82.5%) | 43 (95.56%) | 0.0019 (S) |
| Low | 7 (17.5%) | 0 | |
| Medium | 0 | 0 | |
| High | 0 | 2 (4.44%) | |
| Mean ± SD | 1.57 ± 0.53 | 6 | |