Table 2.
Effect of Aberrant Epression of CD7 on Clinicopathological Characteristics in CN-AML Patients
| Parameter | CD7 | P | ||
|---|---|---|---|---|
| Negative | positive | |||
| Age* (years) | Median (Min-Max) | 44.0 (18-81) | 50.0 (19-70) | 0.06 |
| Gender | Male | 126 (60.0%) | 30 (71.4%) | 0.164 |
| Female | 84 (40.0%) | 12 (28.6%) | ||
| Hb g/dl* | Median (Min-Max) | 7.8 (4-11.9) | 7.0 (6-9.6) | 0.087 |
| WBCs ×109/L* | Median (Min-Max) | 20.0 (1-281) | 21.0 (0.8-56) | 0.646 |
| PLT ×109/L* | Median (Min-Max) | 33.0 (5-529) | 29.4 (12-49) | 0.008 |
| BM blast %* | Median (Min-Max) | 70.0 (24-98) | 70.0 (30-90) | 0.165 |
| FLT3 mutation | Negative | 176 (83.8%) | 14 (33.3%) | <0.001 |
| Positive | 34 (16.2%) | 28 (66.7%) | ||
| Induction remission Response | CR | 150 (73.5%) | 24 (57.1%) | 0.034 |
| Non-CR | 54 (26.5%) | 18 (42.9%) | ||
| Relapse | Non-relapsed | 108 (72.0% ) | 6 (25.0%) | <0.001 |
| Relapsed | 42 (28.0%) | 18 (75.0%) | ||
| Outcome | Alive | 90 (42.9%) | 6 (14.3%) | 0.001 |
| Dead | 114 (54.3%) | 36 (85.7%) | ||
| Cumulative incidence of OS** | 40.30% | 14.30% | <0.001 | |
| Cumulative incidence of DFS** | 54.40% | 0.00% | <0.001 | |
Continuous variables are expressed as median (min-max).* data are compared using Mann-Whitney tests, Chi square test, log rank test ** P1, between CD33 groups; P2, between CD13 groups. **significant (P value < 0.05)