Table 4.
Single-nucleotide Polymorphisms Denoting Sensitivity and Specificity in Predicting Breast Tumor Risk
| Polymorphism type | p depending on the group |
The region under the ROC curve | p depends on the value of the logistic function |
Sensitivity (%) |
Specificity (%) |
|---|---|---|---|---|---|
| rs4646 | p=0.028 | 0.567±0.028 with 95% CI: 0.513-0.622 | p=0.010 | 46.80 | 66.00 |
| rs1065852 | p<0.001 | 0.605±0.028 with 95% CI: 0.551-0.659 | p<0.001 | 93.10 | 23.00 |
| rs4244285 | p=0.002 | 0.579±0.028 with 95% CI: 0.525-0.634 | p<0.001 | 42.10 | 71.50 |
| rs67376798 | p<0.001 | 0.640±0.027 with 95% CI: 0.587-0.692 | p<0.001 | 31.90 | 96.00 |
| rs6504950 | p=0.042 | 0.630±0.027 with 95% CI: 0.587-0.634 | p=0.137 | 77.80 | 28.00 |
| rs2229774 | p=0.001 | 0.530±0.028 with 95% CI: 0.475-0.585 | p<0.001 | 100.00 | 6.00 |
| rs1800056 | p<0.001 | 0.617±0.027 with 95% CI: 0.564-0.671 | p<0.001 | 26.40 | 97.00 |
| rs16942 | p=0.026 | 0.551±0.028 with 95% CI: 0.496-0.606 | p=0.027 | 72.70 | 37.50 |
| rs4987047 | p=0.004 | 0.565±0.028 with 95% CI: 0.510-0.620 | p=0.004 | 75.50 | 37.50 |