Table 2.

Association of Expression of DDIT3 and MGMT (Mean ±SD) with Different Clinicopathological Cum Life Style associated Factor

	N	DDIT3		MGMT
		mRNA expression	P-value	mRNA expression	P-value
Duration of age
10- 39 years	78	0.96±0.82		1.3±1.17
40- 59 years	112	0.97±0.86	0.005	1.31±1.39	0.05
60 - 79 years	27	0.35±0.49		0.57±0.78
80 years & above	2	0.95±1.34		1.18±1.66
Gender
Male	142	0.942±0.90	0.269	1.29±1.32	0.234
Female	77	0.811±0.70		1.07±1.16
Splenomegaly
Mild	108	1.04±0.88	0.015	1.51±1.3	0.001
Moderate	72	0.83±0.81		1.11±1.24
Massive	39	0.602±0.65		0.57±0.74
Disease Stage
Chronic	138	1.03±0.90	0.008	1.57±1.39	0.001
Accelerated	46	0.87±0.68		0.705±0.68
Blast	35	0.38±0.49		0.48±0.75
Smoking Category
Yes	104	0.695±0.83	0.001	0.97±1.03	0.007
No	115	1.07±0.805		1.43±1.42
Smoking Frequency
1-5 times/day	61	0.71±0.81	0.001	0.99±0.96	0.049
6-10 times/day	35	0.58±0.82		0.903±1.08
16-20 times/day	2	0.006±0.005		0.52±0.73
	N	DDIT3		MGMT
		mRNA expression	P-value	mRNA expression	P-value
Smoking Duration
1-10 yrs	30	0.56±0.69	0.01	0.767±0.69	0.037
11-20 yrs	33	0.72±0.92		1.24±1.12
21-30 yrs	37	0.81±0.87		0.95±1.17
31-40 yrs	4	0.62±0.71		0.47±0.87
Alcohol habit
Yes	103	0.825±0.89	0.237	1.02±0.99	0.037
No	116	0.95±0.78		1.38±1.46
Alcohol habit
1-10 yrs	38	0.717±0.91	0.027	1.07±0.93	0.034
11-20 yrs	44	1.03±0.93		1.21±1.08
21-30 yrs	107	0.48±0.58		0.58±0.75
Lab Diagnosis
B3A2	144	0.795±0.825	0.262	1.23±1.26	0.861
B2A2	74	1.08±0.841		1.24±1.30
Drug Resistance
Non Resistant	122	1.15±0.90	0.064	1.74±1.3	0.051
Resistant	40	0.34±0.47		0.235±0.62
Carrier	57	0.74±0.64		0.742±0.62

P<0.05 was considered as statistically significant.