Table 3.

Multinomial Logistic Regression Analysis of Factors associated with the Development Accelerated and Blast Stages in Patients with Chronic CML

	Accelerated		Blast
	OR (95% C.I)	p-value	OR (95% C.I)	p-value
Age	1.323 (1.15-1.522)	0.001	1.478 (1.139-1.918)	0.003
Gender	1.160 (0.343-3.921)	0.811	6.132 (0.506-74.39)	0.154
Hb%	0.824 (0.640 – 1.063)	0.136	1.007 (0.958-1.06)	0.774
Splenomegaly	26.85 (7.423-97.18)	0.001	127.05 (15.15-1063.8)	0.001
WBC count	1.034 (0.85-1.25)	0.73	1.115 (0.905-1.37)	0.306
Platelet	1.051 (0.782-1.413)	0.74	0.264 (0.089-0.785)	0.017
Blast	1.035 (0.961-1.115)	0.059	1.129 (0.998-1.277)	0.054
Promyelocyte	1.150 (0.986-1.341)	0.076	1.282 (1.02-1.613)	0.033
Myelocyte	1.094 (0.963-1.242)	0.016	0.916 (0.670-1.253)	0.584
Metamyelocyte	0.960 (0.862-1.068)	0.045	1.064 (0.846-1.340)	0.596
Smoking Habit	0.974 (0.304-3.124)	0.965	0.003 (0.005-0.348)	0.017
Alcohol Habit	0.235 (0.07-0.785)	0.019	0.02 (0.001-0.359)	0.008
DDIT3 expression regulation	1.022 (0.294-3.553)	0.973	2.215 (0.203-24.13)	0.514
MGMT expression regulation	3.201 (0.895-11.45)	0.074	0.468 (0.030-7.22)	0.587

OR, Odds ratio; C.I, 95% confidence interval