Table 5.

Survival Analysis for Different Clinicopathological Parameter and Life Style Factor under Consideration

Parameter	Grouping	Frequency	Mean estimate	S.E	95% C.I.		P Value
		(N)			Lower Bound	Upper bound
	10-39	63	44.92	0.83	43.28	46.55
Age group	40-59	106	44.12	0.75	42.64	45.6	0.001
	60-79	25	31.84	2.37	27.18	36.49
	80 and above	2	35	9.19	16.98	44.01
Gender	Male	127	42.78	0.78	41.25	44.309	0.515
	Female	69	42.609	1.21	40.23	44.98
Splenomegaly	Mild	95	46.28	0.47	45.34	47.22
	Moderate	63	42.07	1.15	39.81	44.34	0.001
	Massive	38	34.86	1.98	30.98	38..74
Stage	Chronic	117	46.91	0.25	46.41	47.41
	Accelerated	44	42.52	1.09	40.38	44.66	0.001
	Blast	35	28.94	1.9	25.14	32.74
Smoking category	Yes	95	40.68	1.07	38.57	42.79
	No	101	44.63	0.73	43.19	46.06	0.075
Smoking duration	1-10	24	41.79	1.72	38.41	45.16
	11-20	32	43.28	1.63	40.07	46.49	0.009
	21-30	35	38.68	1.96	34.84	42.52
	31-40	4	30.75	5.44	20.07	41.42
Smoking frequency	1-5	53	40.81	1.41	38.03	43.58
	6-10	35	40.65	1.83	37.05	44.25	0.019
	16-20	1	26	0	26	26
Alcohol category	Yes	93	40.25	1.12	38.04	42.47
	No	103	44.94	0.65	43.65	46.22	0.021
Alcohol duration	1-10	30	43.73	1.5	40.79	46.67
	11-20	41	41.8	1.5	38.86	44.74	0.009
	21-30	23	33.3	2.63	28.13	38.47
Giddiness	Yes	50	43.66	1.12	41.44	45.87
	No	145	42.53	0.78	40.99	44.07	0.87
Lab diagnosis	B3A2	132	42.57	0.8	40.99	45.19
	B2A2	63	42.93	1.15	40.67	45.19	0.58
Drug resistance	Non resistant (Homozygous)	107	46.17	0.4	45.38	46.96	0.001
	Resistant (Homozygous)	39	31.1	2.01	27.15	35.05
	Single allele Resistant (Heterozygous)	50	44.38	0.85	42.7	46.05
DDIT3 regulation	Up regulation	104	44.61	0.65	43.33	45.89
	Down regulation	92	40.57	1.15	38.32	42.82	0.2
MGMT regulation	Up regulation	107	45.53	0.56	44.42	46.64
	Down regulation	789	39.33	1.18	37.02	41.65	0.001

Kaplan Meir survival analysis was performed for individual covariates, P<0.05 was considered significant