Table 6.
Hazard Analysis (p<0.05, significant)
| Parameter | Group1/Group 2 | Frequency | P value | Hazard Ratio | 95% C.I. | |
|---|---|---|---|---|---|---|
| (Group 1/ Group 2) | Lower Limit | Upper Limit | ||||
| Age group | 10-39/40-59 | 63/106 | 0.396 | 0.42 | 0.056 | 3.133 |
| 10-39/60-79 | 63/25 | 0.316 | 0.361 | 0.049 | 2.652 | |
| 10-39/ 80 and above | 63/2 | 0.055 | 1.834 | 0.245 | 13.746 | |
| Gender | Male/ Female | 127/69 | 0.518 | 1.185 | 0.707 | 1.986 |
| Splenomegaly | Moderate/Mild | 36/95 | 0.001 | 0.227 | 0.124 | 0.414 |
| Massive/Mild | 38/95 | 0.01 | 0.465 | 0.26 | 0.83 | |
| Stage | Accelerated/Chronic | 44/117 | 0.001 | 1.09 | 0.051 | 0.16 |
| Blast/ Chronic | 35/117 | 0.001 | 2.34 | 0.132 | 0.441 | |
| Smoking duration | 11-20yrs/1-10yrs | 32/24 | 0.079 | 0.313 | 0.086 | 1.142 |
| 21-30yrs/1-10yrs | 35/24 | 0.01 | 0.173 | 0.046 | 0.655 | |
| 31-40yrs/1-10yrs | Apr-24 | 0.13 | 0.385 | 0.112 | 1.325 | |
| Smoking frequency | 6-10times/1-5times | 35/53 | 0.055 | 0.136 | 0.018 | 1.044 |
| 16-20times/1-5times | Jan-53 | 0.051 | 0.128 | 0.016 | 1.006 | |
| Smoking Habit | Yes/No | 95/101 | 0.0079 | 1.54 | 0.951 | 2.494 |
| Alcohol intake | Yes/No | 93/103 | 0.023 | 1.751 | 1.079 | 2.84 |
| Alcohol duration | 11-20yrs/1-10yrs | 41/30 | 0.008 | 1.32 | 1.167 | 2.845 |
| 21-30yrs/1-10yrs | 23/30 | 0.019 | 1.418 | 1.167 | 2.845 | |
| Giddiness | Yes/No | 50/145 | 0.879 | 1.043 | 0.558 | 1.648 |
| Lab diagnosis | B3A2/B2A2 | 132/63 | 0.588 | 0.871 | 0.529 | 1.435 |
| Resistance | NR/R/single allele R | 107/39 | 0.081 | 1.26 | 0.972 | 1.633 |
| DDIT3 Regulation | Up regulation/down regulation | 104/92 | 0.027 | 1.361 | 0.843 | 2.198 |
| MGMT regulation | Up regulation/ down regulation | 107/89 | 0.001 | 2.291 | 1.405 | 3.736 |