Table 1.

Indications, advantages, and disadvantages of TN

Indications	Advantage	Disadvantage
Localizing symptoms (pain, infection, bleeding) that are resistant to medical therapy in a failed graft	Reduction in chronic rejection	Decreased GSR
To create space for re‐transplantation	Beneficial for survival on dialysis	Loss of residual kidney function
To enable complete withdrawal of immunosuppression	Prevention of graft intolerance syndrome	Difficulty in cross‐matching and longer waiting period for re‐transplant
Risk of graft rupture	Withdrawal of immunosuppressants
Graft malignancy		Surgical complications
Refractory anemia with raised CRP