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. 2024 Mar 2;24:300. doi: 10.1186/s12903-024-04074-3

Table 2.

Knowledge, perception and treatment options of MIH. Univariate analysis between DS (Dental students) and DHS (Dental Hygiene students). Multivariate analysis for Gender (female/male), type of center (center of study public/private) and Group of studies.

Q#: Question number of questionnaire.

(*) Statistically significant at 95%.

Univariate Multivariate
Q# KNOWLEDGE DS = 134
n (%)
DHS = 156
n (%)
p value Gender
p value
Type of Center
p value
Group of studies
p value
Q5 Have you heard of Molar Incisor Hypomineralization (MIH)?
-Yes 130 (97%) 88 (56.4%) < 0.001* 0.513 0.005* 0.000*
Q6 Through what source/s have you heard about MIH?
-Scientific publications 55 (41%) 22 (14.1%) < 0.001* 0.495 0.258 0.000*
-Master classes 103 (76.9%) 45 (28.8%) < 0.001* 0.239 0.002* 0.000*
-Conferences and/or courses 33 (24.6%) 10 (6.4%) < 0.001* 0.272 0.268 0.001*
-Information brochures 7 (5.2%) 4 (2.6%) 0.237 0.394 0.226 0.280
-Internet 52 (38.8%) 37 (23.7%) 0.005* 0.567 0.445 0.006*
-Textbooks 49 (36.6%) 23 (14.7%) < 0.001* 0.505 0.693 0.000*
-Clinical practice 93 (69.4%) 22 (14.1%) < 0.001* 0.773 0.760 0.000*
-Others 38 (28.4%) 26 (16.7%) 0.017* 0.217 0.872 0.083
Q7 Do you know the clinical features of MIH?
-Yes 127 (94.8%) 73 (46.8%) < 0.001* 0.114 0.026* 0.000*
Q8 Which teeth do you think are most frequently affected?
-Permanent first molars and permanent incisors 106 (79.1%) 81 (51.9%) < 0.001* 0.762 0.564 0.000*
-Permanent first molars and incisors and temporary second molars 25 (18.7%) 37 (23.7%) 0.295 0.511 0.002* 0.106
-I do not know/not sure 4 (3%) 43 (27.6%) < 0.001* 0.112 0.010* 0.000*
Q9 Do you have difficulty distinguishing the MIH lesion from other lesions or malformations of dental tissues?
-Yes 64 (47.8%) 102 (65.4%) 0.002* 0.617 0.120 0.005*
Q10 With which ones do you have difficulty distinguishing MIH?
-Dental fluorosis 21 (15.7%) 34 (20.7%) 0.185 0.243 0.829 0.313
-Enamel hypoplasia 66 (49.3%) 43 (27.6%) < 0.001* 0.885 0.483 0.000*
-Amelogenesis imperfecta 39 (29.1%) 27 (17.3%) 0.017* 0.526 0.855 0.072
-Dentinogenesis imperfecta 13 (9.7%) 13 (8.3%) 0.684 0.690 0.378 0.851
-Caries 15 (11.2%) 4 (2.6%) 0.003* 0.924 0.233 0.020*
-Other 3 (2.2%) 24 (15.4%) < 0.001* 0.421 0.487 0.010*
Q11 What factors do you think are involved in the etiology of MIH?
-Genetic factors 98 (73.1%) 99 (63.5%) 0.078 0.181 0.689 0.166
-Chronic diseases of the mother during pregnancy 61 (45.5%) 34 (21.8%) < 0.001* 0.076 0.855 0.000*
-Chronic diseases in the child 42 (31.3%) 30 (19.2%) 0.017* 0.115 0.060 0.001*
-Antibiotics/drugs taken by the mother during pregnancy 52 (38.8%) 40 (25.6%) 0.016* 0.467 0.282 0.047*
- Antibiotics/drugs taken by the child 27 (20.1%) 23 (14.7%) 0.224 0.490 0.890 0.074
-Environmental pollutants 34 (25.4%) 15 (9.6%) 0.001* 0.178 0.037* 0.005*
-Acute illnesses affecting the mother during pregnancy 64 (47.8%) 31 (19.9%) < 0.001* 0.587 0.479 0.000*
- Acute illnesses affecting the child 45 (33.6%) 17 (10.9%) < 0.001* 0.199 0.985 0.000*
-Exposure to fluoride 8 (6%) 26 (16.7%) 0.005* 0.725 0.209 0.047*
-None 2 (1.5%) 2 (1.3%) 0.878 0.998 0.288 0.837
-Other 5 (3.7%) 21 (13.5%) 0.004* 0.815 0.908 0.015*
Q12 What do you think is the prevalence of MIH in Spain?
< 5% 9 (6.7%) 7 (4.5%) 0.407 0.016* 0.426 0.792
5–10% 39 (29.1%) 38 (24.4%) 0.362 0.039* 0.394 0.043*
10–20% 37 (27.6%) 32 (20.5%) 0.157 0.212 0.001* 0.347
> 20% 18 (13.4%) 4 (2.6%) < 0.001* 0.632 0.887 0.002*
Not sure 36 (26.9%) 73 (46.8%) < 0.001* 0.413 0.067 0.007*
Q13 Do you think the pattern of caries in teeth with MIH is different from the pattern of normal caries?
Yes 105 (78.4%) 83 (53.2%) < 0.001* 0.636 0.072 0.000*
No 22 (16.4%) 18 (11.5%) 0.230 0.286 0.823 0.030*
Not sure 7 (5.2%) 52 (33.3%) < 0.001* 0.486 0.171 0.000*
Q14 How confident do you feel about diagnosing a tooth with MIH?
-Confident 84 (62.7%) 37 (23.7%) < 0.001* 0.228 0.449 0.000*
Q15 Would you like to receive more training on MIH in your career/training content?
Yes 111 (82.8%) 132 (84.6%) 0.682 0.746 0.269 0.944
Q16 On what aspects of MIH do you think you need to complete your training?
-Diagnosis 72 (53.7%) 93 (59.6%) 0.313 0.906 0.492 0.299
-Etiology 44 (32.8%) 81 (51.9%) 0.001* 0.964 0.689 0.020*
-Treatment 83 (61.9%) 83 (53.2%) 0.134 0.408 0.846 0.635
Others: prevention, long-term prognosis, etc. 61 (45.5%) 90 (57.7%) 0.039* 0.910 0.833 0.081
TREATMENT OPTIONS
NONOPERATIVE AND OPERATIVE
Q17 What preventive (nonoperative) treatment would you apply to MIH lesions without enamel fracture?
-Dental mousse with Recaldent 16 (11.9%) 19 (12.2%) 0.950 0.910 0.052 0.471
-Dental mousse with Recaldent and fluoride 72(53.7%) 24 (15.4%) < 0.001* 0.172 0.968 0.000*
-Professional application of high concentration fluoride varnish (22.600 ppm) 94 (70.1%) 47 (30.1%) < 0.001* 0.492 0.152 0.000*
-Professional application of chlorhexidine varnish. 3 (2.2%) 12 (7.7%) 0.037* 0.620 0.363 0.994
-Sealing of pits and fissures. 49 (36.6%) 36 (23.1%) 0.012* 0.711 0.792 0.008*
-Application of silver diamine fluoride. 10 (7.5%) 9 (5.8%) 0.561 0.093 0.036* 0.970
-Others. 3 (2.2%) 18 (11.5%) 0.002* 0.261 0.295 0.149
Q18 What operative treatment would you apply to teeth affected by MIH with enamel fracture?
-Microabrasion 8 (6%) 11 (7.1%) 0.711 0.629 0.354 0.372
-Resin infiltration. 0 (0%) 1 (0.6%) 0.353 -- -- --
-Conventional glass ionomer 33 (24.6%) 31 (19.9%) 0.330 0.790 0.107 0.086
-Resin-modified glass ionomer 63 (47%) 74 (47.4%) 0.943 0.543 0.669 0.750
-Composite filling 66 (49.3%) 70 (44.9%) 0.456 0.568 0.011* 0.032*
-Silver amalgam filling 1 (0.7%) 3 (1.9%) 0.392 -- -- --
-Preformed crowns 37 (27.6%) 45 (28.8%) 0.816 0.810 0.112 0.026*
-Extraction 8 (6%) 5 (3.2%) 0.257 0.904 0.228 0.236