Table 2. Comparisons of basic characteristics and laboratory indices between anemic and nonanaemic patients with cancer.
| Indices | Cancer without anemia | Cancer with anemia | Statistical value | p-value |
|---|---|---|---|---|
| n | 114 | 170 | ||
| Male(n, %) | 50 (43.9) | 86 (50.6) | 2.412 | 0.120 |
| Age (years) | 54.5 ± 15.9 | 62.1 ± 15.7 | 3.977 | <0.001 |
| BMI (Kg/m2) | 23.59 ± 3.45 | 21.91 ± 3.60 | 1.132 | 0.259 |
| SBP (mmHg) | 126.4 ± 19.3 | 128.4 ± 18.7 | 0.801 | 0.424 |
| DBP (mmHg) | 76.4 ± 10.4 | 74.3 ± 12.5 | 1.19 | 0.235 |
| sCre (mmol/L) | 65.2 (530-75.9) | 64.1 (56.0–77.5) | 0.622 | 0.534 |
| CHOL (mmol/L) | 4.73 ± 0.91 | 4.23 ± 1.16 | 0.380 | 0.705 |
| ALB (g/L) | 40.61 ± 4.10 | 35.01 ± 5.79 | 4.498 | <0.001 |
| Fbg (g/L) | 2.96 ± 0.77 | 3.52 ± 1.25 | 0.811 | 0.418 |
| TSH (U/L) | 1.69 (0.91–3.55) | 2.04 (1.36–2.84) | 1.385 | 0.166 |
| WBC (x109 /L) | 5.92 (4.66–7.16) | 5.62 (4.50–6.79) | 1.894 | 0.058 |
| RBC (x1012 /L) | 4.17 (3.71–4.53) | 3.72 (3.35–4.17) | 11.493 | <0.001 |
| HGB (g/L) | 128.5 (115.3–142.8) | 111.0 (101.0–125.0) | 13.259 | <0.001 |
| HCT (%) | 37.6 (33.6–41.5) | 33.1 (30.0–36.5) | 13.017 | <0.001 |
| MCV (fL) | 90.1 (87.2–93.0) | 90.4 (84.2–93.4) | 1.936 | 0.053 |
| MCH (pg) | 31.0 ± 1.8 | 29.5 ± 4.1 | 3.846 | <0.001 |
| MCHC (g/L) | 342.3 ± 8.6 | 334.2 ± 15.3 | 2.362 | 0.019 |
| RDW-CV (%) | 13. 3(12.8–14.1) | 13.8 (13.0–15.2) | 6.115 | <0.001 |
| PLT (x109 /L) | 216 (176–266) | 205 (158–274) | 0.002 | 0.998 |
| Ret# (x109 /L) | 73 (54–90) | 64 (52–81) | 2.161 | 0.031 |
| HFR (%) | 0.1 (0.0–0.9) | 0.8 (0.0–2.3) | 7.994 | <0.001 |
| MFR (%) | 7.77 ± 2.47 | 11.07 ± 4.24 | 3.319 | 0.001 |
| LFR (%) | 91.92 ± 2.75 | 86.71 ± 6.91 | 3.498 | 0.001 |
| IRF (%) | 8.08 ± 2.75 | 13.30 ± 6.91 | 3.498 | 0.001 |
| RPI | 1.1 (0.7–1.5) | 0.8 (0.6–1.1) | 7.293 | <0.001 |
| RHE (pg) | 28.6 (27.5–29.7) | 28.2 (25.6–29.9) | 1.949 | 0.051 |
| MRV (fL) | 100.6 (96.7–104.2) | 99.2 (90.2–104.9) | 1.862 | 0.063 |
Notes.
Data were presented as mean ± standard deviation, median (P25–P75) or percentage.
- BMI
- body mass index
- SBP
- systolic blood pressure
- DBP
- diastolic blood pressure
- WBC
- white blood cells
- RBC
- red blood cell
- PLT
- platelet
- HCT
- hematocrit
- MCV
- mean corpuscular volume
- MCH
- mean corpuscular hemoglobin
- MCHC
- mean corpuscular hemoglobin concentration
- RDW-CV
- red cell distribution width-coefficient of variation
- RET
- reticulocyte count
- HFR
- high fluorescence reticulocyte
- MFR
- medium fluorescence reticulocyte
- LFR
- low fluorescence reticulocyte
- IRF
- immature reticulocyte fraction
- RPI
- reticulocyte production index
- RHE
- reticulocyte hemoglobin content
- MRV
- mean reticulocyte volume
- alb
- albumin
- Cre
- creatinine
- CHOL
- cholesterol
- TSH
- thyroid stimulating hormone
- Fbg
- fibrinogen.
P values were calculated by student’s t-test, Mann-Whitney U-test and Chi-square test, respectively.