Table 1. Echocardiographic parameters of rats (n ≥ 5).
| Parameter | Units | Control | HFD | Cyy-287 (5 mg/kg) | Cyy-287 (20 mg/kg) |
|---|---|---|---|---|---|
| Diameter;d (LV Trace) | mm | 3.7 ± 0.48 | 4.55 ± 0.26* | 4.4 ± 0.36 | 4.16 ± 0.44 |
| Diameter;s (LV Trace) | mm | 1.94 ± 0.69 | 3.44 ± 0.31*** | 3.2 ± 0.31 | 2.36 ± 0.48# |
| EF (LV Trace) | % | 78.98 ± 12.38 | 48.31 ± 6.56**** | 53.12 ± 5.58 | 74.74 ± 7.15### |
| FS (LV Trace) | % | 48.51 ± 12.2 | 24.34 ± 3.8*** | 27.26 ± 3.55 | 43.77 ± 6.85## |
| V;d (LV Trace) | uL | 59.58 ± 19.02 | 95.2 ± 12.77* | 88.58 ± 16.89 | 77.86 ± 18.31 |
| V;s (LV Trace) | uL | 14.03 ± 12.92 | 49.48 ± 11.01*** | 41.58 ± 9.66 | 20.53 ± 8.55## |
Notes:
EF, Ejection fraction; FS, Fractional shortening; V;d, Left ventricular diastolic volume; V;s, Left ventricular systolic volume.
P < 0.05.
P < 0.001 compared with the control group.
P < 0.0001.
P < 0.05.
P < 0.01.
P < 0.001 compared with the HFD group.