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. Author manuscript; available in PMC: 2024 Mar 3.
Published in final edited form as: Annu Rev Nutr. 2023 May 19;43:25–54. doi: 10.1146/annurev-nutr-062220-112240

Figure 2.

Figure 2

The multifunctional family of mammalian fatty acid (FA)-binding proteins. As described in the text, different FABPs are found to have specific functions within cells via transport of FA or other ligands to various subcellular destinations and via interactions with specific proteins. They are also reported to function in the circulation following noncanonical secretion from the cell. Not all proposed interactions are indicated, e.g., the stable peripheral membrane association of FABP8 in neuronal myelin sheath. Abbreviations: αSyn, α-synuclein; ATGL, adipose triacylglycerol lipase; Cgi-58, comparative gene identification-58; COPII, coat protein complex II; FA, fatty acid; FAAH, fatty acid amide hydrolase; FABP, fatty acid–binding protein; HSL, hormone-sensitive lipase; PCTV, prechylomicron transport vesicle; TF, transcription factor.