TABLE 4.

Vaccination schedule ^a for adult patients treated with chimeric antigen receptor T‐cell (CAR‐T) therapy. ⁹⁹

Vaccines	Pre‐CAR‐T	≥6 months	≥8 months	≥10 months	≥12 months	≥18 months
IIV	Influenza	Influenza
PCV		PCV13	PCV13	PCV13
PPSV23						PPSV23
DTaP		DTaP	Td	Td
HAV		HAV			HAV
HBV		HBV	HBV		HBV
Varicella zoster b					aRZV	aRZV

Abbreviations: aRZV, adjuvant recombinant zoster vaccine; DTaP, higher dose diphtheria, tetanus, and acellular pertussis vaccine; HAV vaccine, hepatitis A virus; HBV vaccine, hepatitis B virus; IIV, inactivated influenza vaccine; PCV, pneumococcal conjugate vaccine; PPSV23, pneumococcal 23‐valent polysaccharide vaccine; Td, tetanus–diphtheria.

^a This schedule was published prior to the availability of coronavirus disease 2019 (COVID‐19) vaccines. Revaccination with a primary course of three mRNA COVID‐19 vaccines is now recommended for patients following CAR‐T therapy. ⁷⁵

^b Seropositive patients.