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Apparent Km and Vmax values for tumor fumarase.
| Drug dose mg/kg | Km (mM) | Vmax (mM/min) |
|---|---|---|
| Untreated | 0.98 | 0.02 |
| 0.1 | 1.18 | 0.03 |
| 0.4 | 0.88 | 0.05 |
| 0.8 | 0.95 | 0.07 |
Note: The apparent Km of tumor fumarase for fumarate and the Vmax at different injected drug concentrations were determined by fitting the data shown in Figure 2 to the Michaelis–Menten equation.
