TABLE 3.
Cyclin‐dependent kinase | Binding partner | Roles in cell cycle | Roles in transcription | Selected additional roles |
---|---|---|---|---|
Cdc2 | Cdc13, Cig1, Cig2, Puc1, Pas1, Pch1, Rem1 | Governs cell cycle commitment at START in G1; orchestrates mitosis and determines its timing (Beach et al., 1982; Coudreuse & Nurse, 2010; Fisher & Nurse, 1996; Gutiérrez‐Escribano & Nurse, 2015; Martín‐Castellanos et al., 1996, 2000; Nurse, 1975; Nurse & Bissett, 1981; Reymond et al., 1993) |
Required for Cdc10/Sct1 transcription complex formation (Connolly et al., 1997) Inhibits Ste11 (Kjærulff et al., 2007) |