Table 3.
Bleeding events with surgery risk status, prophylaxis plan, and bleeding treatment.
| Surgical procedure | Risk level for the procedure | Medication plan for the procedure | Documented noncompliance | Bleeding events | ISTH severity | Medications needed |
|---|---|---|---|---|---|---|
| IUD insertion | Minor | Tranexamic acid 1300 mg (24.6 mg/kg) 3 times daily for 2 d | Yes | Call to nurses for vaginal bleeding | Minor | Tranexamic acid |
| IUD insertion | Minor | Tranexamic acid 1300 mg (27 mg/kg) 3 times daily for 3 d | No | Call to nurses for vaginal bleeding. Need for unplanned medication | Clinically relevant nonmajor bleeding | Tranexamic acid |
| IUD insertion | Minor | Tranexamic acid 1300 mg (18.5 mg/kg) 3 times daily for 2 d and VWF concentrate 28 units/kg before surgery | No | Call to nurses for vaginal bleeding. Unplanned medication | Clinically relevant nonmajor bleeding | VWF concentrate |
| IUD insertion | Minor | None | No | Call to nurses for vaginal bleeding. Need for unplanned medication | Clinically relevant nonmajor bleeding | Tranexamic acid |
| IUD insertion | Minor | Tranexamic acid 1300 mg (18 mg/kg) 3 times daily for 2 d | No | Call to nurses for vaginal bleeding | Minor | None |
| Tympanostomy tube replacement and dental debridement | Minor | Tranexamic acid 325 mg (17.6 mg/kg) twice daily for 1 d | No | Call to nurses | Minor | None |
| Nasal endoscopy with inferior turbinate reduction | Minor | Aminocaproic acid 30 mg/kg 4 times daily × 2 d DDAVP IN × 1 before the procedure | Yes | Surgical site bleeding. ER visit for bleeding. Need for unplanned medication | Clinically relevant nonmajor bleeding | Aminocaproic acid |
| Tonsillectomy and adenoidectomy | Major | Tranexamic acid 650 mg (15.5 mg/kg) 3 times daily × 10 d DDAVP IN × 1 before the procedure | No | ER visit and unplanned hospitalization for bleeding. Need for unplanned medication. Drop in hemoglobin >2 g/dL | Major | DDAVP, tranexamic acid |
BAT, bleeding assessment tool; BS, bleeding score; DDAVP, desmopressin; ISTH, International Society on Thrombosis and Haemostasis; VWF, von Willebrand factor; RCo, ristocetin cofactor.
DDAVP, desmopressin; ER, emergency room; IN, intranasal; ISTH, International Society of Thrombosis and Haemostasis; IUD, intrauterine device; VWF, von Willebrand factor.