Table 1.

Correction methods used in the absence of a gold standard measurement of AG₉₀

Article section	Acronym	Meaning
Overall	AG90	Perfect measurement of mean glycemia over 90 days for which no gold standard is available.
CGM Analysis	eAG90	Correction of average glucose calculated over 90 days of CGM with addition of representative CGM sensor bias.
	eAGCGM	Estimate of glycemia obtained from a time-weighted average of CGM collected over an arbitrary period of time. Estimated error distributions for eAGCGM depend on monitoring duration and are shown in Fig. 2A.
HbA1c Analysis	eAG90	Correction of the average glucose obtained with addition of representative HbA1c assay error to the average glucose calculated from the following expression, which assumes perfect knowledge of MRBC and HbA1c (HbA1c0 is HbA1c level in the youngest RBCs; kg is the glycation rate constant; HbA1c (IFCC) is HbA1c in IFCC units; see Supplementary Methods for more details):
	eAGA1c	Average glucose estimate, obtained from a single HbA1c measurement through the ADAG equation (below). Estimated error distributions for eAGA1c depend on HbA1c (Fig. 2E).