Table 2.

The diagnosis values of CCL20 and AFP.

Biomarkers	Cut-off	AUC (95%CI)	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)
HCC versus healthy control
AFP	7.55	0.9581(0.9254–0.9908)	82.89	97.37	98.44	74
CCL20	15.43	0.8591(0.7932–0.9250)	73.42	86.84	92.06	61.11
Combination	10.34	0.9675(0.9411–0.9938)	88.16	97.37	98.53	80.43
HCC versus non-HCC
AFP	7.55	0.9171(0.8769–0.9573)	82.89	86.6	82.89	86.6
CCL20	23.37	0.7141(0.6385–0.7897)	67.09	70.1	65.43	72.34
Combination	56.18	0.9021(0.8581–0.9460)	91.67	75.26	73.33	92.4