Table 4.

Unmatched multivariate linear regression for initial cranioplasty and long-term total direct costs ($).

Variable	Standardized Coefficients	95% confidence intervals		P value
		Lower bound	Upper bound
Initial surgery total direct costs
Custom CP	0.20	0.13	0.26	<0.01
Smoker	−0.02	−0.08	0.04	0.52
HTN	−0.03	−0.09	0.04	0.44
Age	0.04	−0.03	0.11	0.23
Male sex	0.00	−0.06	0.06	0.93
GCS score	−0.01	−0.08	0.05	0.68
Reason for HC (stroke)	−0.01	−0.07	0.05	0.80
CP surface area (cm2)	0.02	−0.04	0.08	0.51
Time from HC to CP (days)	0.02	−0.04	0.08	0.48
CP operative duration (min)	0.03	−0.03	0.03	0.30
Length of stay (days)	0.92	0.86	0.98	<0.01
Initial plus long-term total direct costs
Custom CP	0.10	−0.03	0.22	0.13
Smoker	−0.02	−0.14	0.10	0.75
Hypertension	0.02	−0.11	0.16	0.76
Age	0.13	0.00	0.27	0.04
Male sex	−0.10	−0.22	0.03	0.12
GCS score	−0.02	−0.14	0.11	0.80
Reason for HC (stroke)	0.00	−0.12	0.13	0.97
CP surface area (cm2)	0.07	−0.05	0.20	0.25
Time from HC to CP (days)	−0.03	−0.16	0.09	0.59
CP operative duration (min)	0.13	0.01	0.25	0.03
Length of stay (days)	0.63	0.51	0.75	<0.01

For initial cranioplasty costs, R² = 0.87, p < 0.01. For long-term cranioplasty costs, R² = 0.50, p < 0.01.

CP, cranioplasty; GCS, Glasgow Coma Scale; HC, hemicraniectomy; HTN, hypertension.

Boldface font indicates statistical significance.