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. 2023 Dec 19;49(3):710–721. doi: 10.1007/s00261-023-04130-6

Table 4.

Diagnostic performance for MVI of cHCC-CCA

AUC (95% CI) Sensitivity Specificity Accuracy PPV NPV
AAPR 0.560 (0.456, 0.663) 15.2 (9/59) 96.7 (58/60) 56.3 (67/119) 81.8 (9/11) 53.7 (58/108)
ANRI 0.585 (0.483, 0.688) 25.4 (15/59) 91.7 (55/60) 58.9 (70/119) 75.0 (15/20) 55.6 (55/99)
Non-smooth margin 0.614 (0.512–0.715) 66.1 (39/59) 60.0 (34/60) 61.3 (73/119) 60.0 (39/65) 63.0 (34/54)
Arterial phase peritumoral enhancement 0.740 (0.648, 0.831) 78.0 (46/59) 70.0 (42/60) 73.9 (88/119) 71.9 (46/64) 76.4 (42/55)
Imaging model 0.759 (0.671, 0.847) 78.0 (46/59) 70.0 (42/60) 73.9 (88/119) 71.9 (46/64) 76.4 (42/55)
Combined model 0.802 (0.724, 0.881) 83.1 (49/59) 66.7 (40/60) 74.8 (89/119) 71.0 (49/69) 80.0 (40/50)

Imaging model model only using imaging data, Combined model combined inflammatory biomarkers with imaging features, AUC area under the curve, PPV positive predictive value, NPV negative predictive value