Table 2.

Grading system for CS (Davis et al. 2013)

A: Distribution and extent of crusting	1	Wrists, web spaces, feet only (< 10% Total Body Surface Area)
	2	As “1” + forearm, lower legs, buttocks, trunk (or 10–30% TBSA)
	3	As “2” + scalp (or > 30% TBSA)
B: Crusting/Shedding	1	Mild crusting (< 5mm depth), minimal skin shedding
	2	Moderate (5-10mm) crusting, moderate skin shedding
	3	Severe (> 10mm), severe skin shedding
C: Past episodes	1	No previous episodes
	2	1–3 hospitalizations for CS (or depigmentation of elbow, knees)
	3	> 4 previous hospitalizations (or depigmentation as above + legs/back, or residual skin thickening)
D: Skin condition	1	No cracking or pyoderma
	2	Multiple pustules or weeping sore or superficial skin cracking
	3	Deep skin cracking with bleeding, widespread exudates
Grading: - Grade 1: total score 4–6 - Grade 2: total score 7–9 - Grade 3: total score 10–12 Treatment: - Grade 1: 3 doses of IVM (days 0, 1, 7) - Grade 2: 5 doses of IVM (days 0, 1, 7, 8, 14) - Grade 3: 7 doses of IVM (days 0, 1, 7, 8, 14, 21, 28)