Table 3.
Association of CYP1A2 and CYP3A4 genetic polymorphisms
| Gene | dbSNP | Genotype | Cancer (%) | Control (%) | P-Value | OR (95% CI) |
|---|---|---|---|---|---|---|
| ADSL | rs3788579 | TT | 52 | 24 | Ref | Ref = 1 |
| CC | 27 | 56 | 0.000 | 1.788 (1.451–2.202) | ||
| CT | 21 | 20 | 0.000 | 0.553 (0.445–0.686) | ||
| CYP1A2 | rs17861162 | CC | 54 | 69 | Ref | Ref = 1 |
| GG | 9 | 2 | 0.022 | 0.70 (0.52–0.93) | ||
| CG | 37 | 29 | 0.026 | 1.34 (1.10–1.64) |
| Gene | allele | Cancer (%) | Control (%) | P-Value | OR (95% CI) |
|---|---|---|---|---|---|
| ADSL | C | 37.5 | 66.0 | Ref | Ref = 1 |
| T | 62.5 | 34.0 | 0.000 | 3.235 (2.149–4.872) | |
| CYP1A2 | C | 72.5 | 83.5 | Ref | Ref = 1 |
| G | 27.5 | 16.5 | 0.008 | 1.92 (1.18–3.11) |
Pationts: 100, Controls: 100, P-Value ≤ 0.05