Table 3.
Inhibition rates measured by the xCELLigence RTCA method after 24 hours of treatment of MCF-7 cells with different combination doses calculated over different percentages of PTX and OLE IC50 doses.
| % IC50 | Inhibition (%) |
|---|---|
| 10% (OLE 23 µM+PTX 0.75 µM) | 65.57 ± 3.19**** |
| 20% (OLE 46 µM+PTX 1.5 µM) | 49.35 ± 0.96**** |
| 30% (OLE 69 µM+PTX 2.25 µM) | 46.18 ± 1.85**** |
| 40% (OLE 92 µM+PTX 3 µM) | 50.72 ± 1.59**** |
| 50% (OLE 115 µM+PTX 3.75 µM) | 43.56 ± 0.39**** |
| 75% (OLE 172.5 µM+PTX 5.63 µM) | 49.69 ± 5.28**** |
| 100% (OLE 230 µM+PTX 7.5 µM) | 42.43 ± 2.17**** |
Note: ****p < 0.0001 when compared with the control.