Table 3.

Effect of CCl₄ and additive used on biochemical parameters¹ at 28 and 42 d.

		AST (U/L)		ALT (U/L)		ALP (U/L)		GGT (U/L)		TP (g/dL)		Alb. (g/dL)
		28 d	42 d	28 d	42 d	28 d	42 d	28 d	42 d	28 d	42 d	28 d	42 d
Challenge	Additive
CCl4 0 mL/kg BW	None	228	261	10b	77	17888	3816	18.3	22.6	2.39	3.0	0.50	1.0
	Silymarin	314	196	44a	66	13177	6269	20.5	18.9	2.30	2.9	0.79	0.8
	CA-PFA	230	123	35a	34	12649	5518	21.4	18.5	2.16	2.8	0.84	0.9
CCl4 1 mL/kg BW	None	251	110	8b	41	13765	6456	18.9	18.9	2.25	2.6	0.65	1.0
	Silymarin	266	209	9b	48	25523	5105	19.3	21.0	2.28	2.8	0.55	0.8
	CA-PFA	253	232	9b	74	21950	5345	21.0	22.4	2.38	2.7	0.58	0.9
	SEM (n = 8)	83	131	17	45	10535	3065	3.8	7.67	0.35	0.31	0.20	0.15
Main effects
CCl4	0 mL/kg BW	257	193	29a	59	14571	5201	20.0	20.0	2.28	2.9	0.71	0.9
	1 mL/kg BW	256	184	9b	54	20413	5635	19.7	20.7	2.30	2.7	0.59	0.9
	SEM (n = 24)	84	137	19	46	10811	3051	3.82	7.52	0.35	0.30	0.23	0.16
Additive	None	239	186	9b	59	15826	5136	18.6	20.7	2.32	2.8	0.58	1.0
	Silymarin	290	203	26a	57	19350	5687	19.9	19.9	2.29	2.8	0.67	0.8
	CA-PFA	241	177	22ab	54	17299	5431	21.2	20.4	2.27	2.7	0.71	0.9
	SEM (n = 16)	82	138	21	46	11240	3084	3.70	7.60	0.35	0.32	0.23	0.14
Effect (P-value)
CCl4		0.974	0.798	<0.001	0.731	0.062	0.626	0.775	0.732	0.871	0.054	0.055	0.847
Additive		0.160	0.852	0.014	0.948	0.640	0.879	0.158	0.954	0.921	0.806	0.187	0.016
CCl4 x Additive		0.382	0.205	0.022	0.052	0.074	0.203	0.794	0.353	0.367	0.328	0.101	0.837

^a–bMeans in the same column with different superscripts are different (P < 0.05)

¹AST: Aspartate Amino Transferase; ALT: Alkaline Amino Transferase; GGT: Gamma Glutamyl Transferase; ALP: Alkaline Phosphatase; TP: Total Protein; Alb: Albumin