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. 2024 Feb 19;18:1330695. doi: 10.3389/fnins.2024.1330695

Table 2.

Subcortical structural volume analysis investigating the interaction between the study group and measures of sleep disturbance.

Dependent variable: volume of subcortical structure Interaction term
Study group × ESS Study group × ISI
β Unadjusted value of p FDR adjusted value of p β Unadjusted value of p FDR adjusted value of p
Left thalamus 0.14 0.45 0.84 0.21 0.13 0.68
Left caudate −0.26 0.19 0.68 0.02 0.91 0.91
Left putamen 0.21 0.35 0.75 0.55* 0.001 0.02
Left pallidum 0.05 0.79 0.91 0.06 0.69 0.89
Left hippocampus −0.08 0.70 0.89 −0.39 0.009 0.09
Left amygdala 0.13 0.52 0.85 −0.19 0.22 0.68
Left accumbens 0.03 0.88 0.91 0.04 0.78 0.91
Right thalamus 0.09 0.66 0.89 0.16 0.30 0.71
Right caudate −0.14 0.50 0.85 0.02 0.88 0.91
Right putamen 0.26 0.22 0.68 0.51* 0.001 0.02
Right pallidum 0.10 0.63 0.89 0.19 0.26 0.68
Right hippocampus −0.31 0.15 0.68 −0.24 0.15 0.68
Right amygdala 0.22 0.27 0.68 −0.11 0.44 0.84
Right accumbens −0.11 0.63 0.89 −0.04 0.83 0.91

Independent variables: Age, sex, estimated total intracranial volume, study group, sleep disturbance measure (i.e., ESS and ISI), study group × sleep disturbance measure (interaction term). Study groups are encoded as follows: Shift workers: 1; non-shift workers: 0. *FDR adjusted value of p < 0.05. ESS, Epworth Sleepiness Scale; ISI, Insomnia Severity Index; FDR, False Discovery Rate.