Table 1.

SVD and BVF definitions according to the VARC-3 committee (12).

SVD	Definition	Intrinsic permanent changes to the prosthetic valve, including wear and tear, leaflet disruption, flail leaflet, leaflet fibrosis and/or calcification, or strut fracture or deformation
	Stages	Stage 1: Morphological valve deterioration Evidence of structural valve deterioration without significant hemodynamic changes
		Stage 2: Moderate hemodynamic valve deterioration increase in mean transvalvular gradient ≥10 mmHg, resulting in mean gradient ≥20 mmHg with concomittant decrease in effective orifice area ≥0.3 cm2 or ≥25% and/or decrease in Doppler velocity index ≥0.1 or ≥20% compared with echocardiographic assessment performed 1–3 months post-procedure, OR new occurrence or increase of≥1 graded of intraprosthetic AR resulting in≥moderate AR.
		Stage 3: Severe hemodynamic valve deterioration Increase in mean transvalvular gradient≥20 mmHg resulting in mean gradient≥30 mmHg with concomitant decrease in effective orifice area≥0.6 cm2 or≥50% and/or decrease in Doppler velocity index≥0.2% or≥40% compared with echocardiographic assessment performed 1–3 months post-procedure, OR new occurrence, or increase of≥2 grades,d of intraprosthetic AR resulting in severe AR.
BVF	Stage 1	Any bioprosthetic valve dysfunction associated with clinically expressive criteria (new-onset or worsening symptoms, LV dilation/hypertrophy/dysfunction, or pulmonary hypertension) or irreversible Stage 3 haemodynamic valve deterioration
	Stage 2	Aortic valve reoperation or re-intervention
	Stage 3	Valve-related death