Table 3.

Multivariate analysis for PFS of R/M HNSCC patients.

Factors	Sig.	Exp(B)	95.0%Cl for Exp(B)
			Lower	Upper
Sex (Male vs Female)	.616	.836	.416	1.681
Age (≥60vs<60)	.684	1.152	.584	2.273
Primary tumor site (Oral vs Oropharyngeal)	.615	1.411	.369	5.392
Recurrence pattern	.142	.616	.323	1.175
HPV infection (Positive vs Negative)	.743	1.488	.138	15.991
ECOG PS (1 vs 2)	.061	2.386	.960	5.935
First-line therapy vs ≥2nd line therapy	.001	.265	.118	.592
irAEs vs No irAEs	.016	.297	.110	.800