Table 4.
MIC and MBC results of HZQYF on different H. pylori strains.
| H. pylori strains | Drug sensitivitya | HZQYF | CLR | ||
|---|---|---|---|---|---|
| MICb (μg/mL) | MICc (μg/mL) | MBC (μg/mL) | MIC (μg/mL) | ||
| ATCC 43504 | R (MTZ) | 160 | 160 | 320 | 0.016 |
| ATCC 700392 | S | 160 | 160 | 320 | 0.004 |
| SS1 | S | 160 | 160 | 320 | 0.016 |
| CSO1 | R (CLR) | 160 | 160 | 320 | <0.002 |
| QYZ-001 | R (MTZ) | 160 | 160 | 320 | < 0.4 |
| QYZ-003 | R (CLR, MTZ, LEF) | 80 | 80 | 160 | 12.8 |
| QYZ-004 | R (CLR, MTZ, LEF, AMO) | 80 | 80 | 160 | 1.6 |
| ICDC111001 | R (MTZ, LEF) | 160 | 160 | 320 | 1.6 |
a S drug sensitive, R drug resistant. The European Committee on Antimicrobial Susceptibility Testing’s (EUCAST 2019) breakpoint values for antibiotic resistance were established. The drug sensitivity information of these strains has been merged with those stated by Shen et al.
b Using microbroth dilution method.
c Using agar dilution method.