Table II.
Bivariate and multivariate logistic regression models of factors associated with UCA with controlled asthma as a reference and UCA with steps 1 and 2 treatment with controlled asthma steps 1 and 2 treatment as reference
| Characteristic | All |
Girls |
Boys |
Aged 6-11 y |
Aged 12-17 y |
|
|---|---|---|---|---|---|---|
| Crude OR (95% CI) | Adjusted OR (95% CI) | Adjusted OR (95% CI) | Adjusted OR (95% CI) | Adjusted OR (95% CI) | Adjusted OR (95% CI) | |
| Model A: UCA (controlled asthma as a reference) | ||||||
| Female sex | 1.28 (1.14-1.44) | 1.29 (1.15-1.45) | 0.94 (0.80-1.11) | 1.81 (1.53-2.15) | ||
| Older age | 1.04 (1.02-1.05) | 1.02 (1.00-1.04) | 1.09 (1.06-1.12) | 0.98 (0.95-1.00) | ||
| Normal weight | REF | REF | REF | REF | REF | REF |
| Overweight | 1.11 (0.95-1.29) | 1.10 (0.95-1.29) | 1.10 (0.86-1.42) | 1.12 (0.92-1.37) | 1.16 (0.93-1.43) | 1.07 (0.85-1.34) |
| Obesity | 1.46 (1.14-1.86) | 1.43 (1.12-1.83) | 1.19 (0.79-1.79) | 1.64 (1.20-2.24) | 1.59 (1.13-2.22) | 1.33 (0.92-1.91) |
| Treatment steps 1-2 | REF | REF | REF | REF | REF | REF |
| Treatment step 3 | 1.34 (1.18-1.52) | 1.28 (1.12-1.46) | 1.09 (0.89-1.35) | 1.43 (1.20-1.69) | 1.38 (1.15-1.65) | 1.19 (0.98-1.44) |
| Treatment steps 4-5 | 1.36 (1.15-1.62) | 1.32 (1.10-1.57) | 1.29 (0.96-1.71) | 1.37 (1.09-1.72) | 1.53 (1.16-2.01) | 1.20 (0.95-1.51) |
| Model B: UCA steps 1 and 2 (controlled asthma steps 1-2 as a reference) | ||||||
| Female sex | 1.32 (1.13-1.55) | 1.32(1.13-1.55) | 0.94 (0.76-1.16) | 2.18 (1.69-2.80) | ||
| Older age | 1.05 (1.03-1.08) | 1.04 (1.02-1.07) | 1.12 (1.08-1.16) | 0.99 (0.96-1.02) | ||
| Normal weight | REF | REF | REF | REF | REF | REF |
| Overweight | 1.13 (0.92-1.40) | 1.13 (0.91-1.39) | 1.18 (0.85-1.64) | 1.13 (0.86-1.49) | 1.18 (0.90-1.54) | 1.09 (0.78-1.53) |
| Obesity | 1.25 (0.88-1.78) | 1.24 (0.87-1.77) | 1.03 (0.58-1.83) | 1.48 (0.94-2.34) | 1.42 (0.90-2.22) | 1.06 (0.59-1.91) |
UCA defined as an ACT score of 19 or lower and/or 2 or more exacerbations in the past year and/or an FEV1 value less than 80% predicted. Normal weight reference to overweigh and obesity. Age was entered as a continuous variable. Boldface indicates statistical significance.
REF, Reference.