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Comparison of gDNA-PCR MRD and FCM-MRD based on FAB classification. A threshold of ≥0.1% was used to define MRD positivity. The presence of maturation leads to reduced concordance of gDNA-PCR MRD and FCM-MRD (P=0.066). Statistical analysis was done using GraphPad Prism 8.3.0 and χ2 tests. gDNA: genomic DNA; PCR: polymerase chain reaction; MRD: measurable residual disease; FCM: flow cytometry; FAB: French-American-British.
