Table 3.
Calculated sensitivity and specificity (and 95% confidence intervals) for the GeneXpert (using random effects model)
| Chlamydia | |||
| Country | Valid Cases | Sensitivity (95% Confidence Intervals) | Specificity (95% Confidence Intervals) |
| Morocco | 383 | 70.1% (58.6–80.0) | 97.7% (95.3–99.1) |
| Guatemala (Site 1) | 86 | 82.4% (56.6–96.2) | 100% (94.8–100) |
| South Africa | 785 | 91.4% (87.6–94.3) | 96.9% (95.0-98.3) |
| Pooled estimate | 1254 | 83.7% (69.2–92.1) | 97.4% (96.1-98.3%) |
| Gonorrhoea | |||
| Country | Valid Cases | Sensitivity (95% Confidence Intervals) | Specificity (95% Confidence Intervals) |
| Morocco | 388 | 90.9% (58.7–99.8) | 99.7% (98.5–100) |
| Guatemala (Site 1) | 86 | 100% (15.8–100) | 98.8% (93.5–100) |
| South Africa | 779 | 90.4% (84.6–94.5) | 98.4% (97.1–99.2) |
| Pooled estimate | 1253 | 90.5% (85.1–94.1) | 99.1% (97.6–99.6) |
| Trichomoniasis | |||
| Country | Valid Cases | Sensitivity (95% Confidence Intervals) | Specificity (95% Confidence Intervals) |
| Morocco | 393 | 59.7% (51.5–67.6) | 98.8% (96.4–99.8) |
| Guatemala (Site 1) | 84 | 91.7% (61.5–99.8) | 100% (95.1–100) |
| South Africa | 786 | 66.1% (57.1–74.4) | 98.8% (97.6–99.5) |
| Australia | 69 | 84.6% (54.6–98.1) | 100% (94.6–100)) |
| Pooled estimate | 1332 | 64.7% (58.1–70.7) | 99.0% (98.1–99.4) |