Table 2.
Baseline characteristics of malaria patients and healthy controls. The means of selected parameters were compared in three groups using the ANOVA test (P valuea) or in two groups, SM and UM using the Student test (P valueb). Values were statistically significant when p < 0.05
| Characteristics | CTR (n = 48) | UM (n = 54) | SM (n = 71) | P valuea | P valueb |
|---|---|---|---|---|---|
| Age, (M ± SD, year) | 30.54 (16.14) | 13.72 (17.56) | 20.76 (20.17) | P < 0.0001 | 0.07 |
| Gender, (%) | |||||
| Male | 21 (43.75) | 19 (35.20) | 37 (52.11) | ||
| Female | 27 (56.25) | 31 (57.40) | 31 (43.67) | ||
| Hb (M ± SD, g/dl) | 12.95 (1.930) | 12.49 (2.855) | 8.631 (3.150) | P < 0.0001 | P < 0.0001 |
| Hematocrit (M ± SD, %) | 38.76 (5.762) | 37.65 (8.382) | 25.22 (9.631) | P < 0.0001 | P < 0.0001 |
| MCV (M ± SD, fL) | 83.25 (5.687) | 88.60 (12.90) | 79.14 (13.25) | P = 0.0009 | P = 0.007 |
| RBCs (M ± SD, × 106/µL) | 4.699 (0.632) | 4.145 (0.796) | 3.149 (1.162) | P < 0.0001 | P < 0.0001 |
| MCHC (M ± SD, pg/cell) | 33.60 (0.626) | 33.74 (3.159) | 33.33 (1.536) | P = 0.6685 | P = 0.289 |
| Leucocyte (M ± SD, × 103/µL) | 5.933 (2.405) | 8.217 (4.351) | 12.40 (6.952) | P < 0.0001 | P = 0.0008 |
| Neutrophil (M ± SD, %) | 43.71 (10.64) | 59.95 (15.36) | 54.05 (25.60) | P = 0.0068 | P = 0.766 |
| Lymphocyte (M ± SD, %) | 43.21 (10.89) | 29.27 (13.13) | 22.86 (17.03) | P < 0.0001 | P = 0.538 |
| Monocyte (M ± SD, %) | 7.970 (2.887) | 7.312 (5.597) | 6.662 (4.691) | P = 0.5191 | P = 0.663 |
| Eosinophil (M ± SD, %) | 4.210 (3.829) | 3.2 (2,815) | 0.461 (0.451) | P < 0.0001 | P = 0.0002 |
| Basophil (M ± SD, %) | 0.8925 (0.558) | 0.717 (0.575) | 0.6858 (0.729) | P = 0.3369 | P = 0.239 |
M ± SD mean ± Standard Deviation, CTR Control, UM Uncomplicated Malaria, SM Severe Malaria, Hb Hemoglobin, MCV Mean Corpuscular Volume, RBCs Red Blood Cells, MCHC Mean Corpuscular Hemoglobin Concentration