Table 3.
Expression of studied genes in MDA-MB-231 cell line
| MDA-MB-231 | ||||||
|---|---|---|---|---|---|---|
| Normoxic | Hypoxic | |||||
| Treated with DHA | Treated with CoCl2 | Treated with DHA and CoCl2 | ||||
| Fold change | P-value* | Fold change | P-value** | Fold change | P-value*** | |
| CD39 | -21.54 | < 0.0001 | 1.931994 | < 0.0001 | -3.70 | < 0.0001 |
| CD73 | -3.2329 | 0.0001 | 13.36898 | < 0.0001 | -5.25 | < 0.0001 |
| CD47 | -1.2378 | 0.0324 | 19.86097 | < 0.0001 | -1.78 | < 0.0001 |
| CD80 | -2.1281 | 0.0006 | 18.38235 | < 0.0001 | -6.32 | < 0.0001 |
| PD-L1 | -2.4426 | < 0.0001 | 5.52975 | < 0.0001 | -10.27 | < 0.0001 |
| B7-H3 | -40.98 | < 0.0001 | 2.191541 | < 0.0001 | -24.91 | < 0.0001 |
| B7-H4 | -2.4056 | < 0.0001 | 13.7931 | < 0.0001 | -16.91 | < 0.0001 |
*: compared control with DHA treated group
**: compared control with CoCl2 treated group
***: compared CoCl2 treated group with DHA + CoCl2 treated group