Table 6.
Expression of studied genes in exosomes- derived BT-474 cell line
| Exo-BT-474 | ||||||
|---|---|---|---|---|---|---|
| Normoxic | Hypoxic | |||||
| Treated with DHA | Treated with CoCl2 | Treated with DHA and CoCl2 | ||||
| Fold change | P-value* | Fold change | P-value** | Fold change | P-value*** | |
| CD39 | -1.8856 | < 0.0001 | 1.924928 | < 0.0001 | -2.41 | < 0.0001 |
| CD73 | -8.98 | < 0.0001 | 1.85701 | < 0.0001 | -2.54 | < 0.0001 |
| CD47 | -1.39 | 0.0016 | -1.21 | 0.0240 | -1.07 | 0.7316 |
| CD80 | -1.79 | 0.0012 | 2.309469 | < 0.0001 | -3.02 | < 0.0001 |
| PD-L1 | -1.19 | 0.1186 | 1.869858 | < 0.0001 | -2.20 | < 0.0001 |
| B7-H3 | -2.064 | < 0.0001 | 2.184837 | < 0.0001 | -3.44 | < 0.0001 |
| B7-H4 | -2.428 | < 0.0001 | 1.897533 | < 0.0001 | -3.66 | < 0.0001 |
*: compared control with DHA treated group
**: compared control with CoCl2 treated group
***: compared CoCl2 treated group with DHA + CoCl2 treated group